NCIt related terms : recombinant fowlpox-CEA-MUC-1-TRICOM vaccine;
NCIt definition : A cancer vaccine comprised of a recombinant fowlpox viral vector encoding the carcinoembryonic
antigen (CEA), MUC-1, a transmembrane glycoprotein secreted by glandular epithelial
tissues, and TRICOM, comprised of three co-stimulatory molecule transgenes (B7-1,
ICAM-1 and LFA-3). This agent may enhance CEA and MUC-1 presentation to antigen-presenting
cells (APC) and may activate a cytotoxic T-cell response against CEA- and MUC-1-expressing
tumor cells.;
Alternative definition : NCI-GLOSS: A cancer vaccine made with a form of a chicken virus that does not cause
disease in humans. It is being studied in the treatment of some types of cancer. The
virus is changed in the laboratory to make human proteins that may help immune cells
in the body kill tumor cells.;
CAS number : 685563-14-8;
Drug name : PANVAC-F;
NSC code : 727027;
Codes from synonyms : CDR0000572218; CDR0000468788;