" /> Inalimarev - CISMeF





Preferred Label : Inalimarev;

NCIt synonyms : rVaccinia-CEA(D609)/MUC1(L93)/TRICOM Vaccine; Vaccinia-CEA-MUC1-TRICOM Vaccine; rVaccinia-CEA D609 MUC1 L93 TRICOM;

NCIt related terms : recombinant vaccinia-CEA-MUC-1-TRICOM vaccine; PANVAC-V;

NCIt definition : A cancer vaccine comprised of a recombinant vaccinia viral vector encoding the carcinoembryonic antigen (CEA), MUC-1 (mucin-1), a transmembrane glycoprotein secreted by glandular tissues, and TRICOM, comprised of the three co-stimulatory molecule transgenes B7-1, ICAM-1 and LFA-3. Upon administration, inalimarev may enhance CEA and MUC-1 presentation to antigen presenting cells (APC) and may activate a cytotoxic T lymphocyte (CTL) response against CEA- and MUC-1-expressing tumor cells.;

Alternative definition : NCI-GLOSS: A cancer vaccine made with a form of vaccinia virus that does not cause disease in humans. It is being studied in the treatment of some types of cancer. The virus is changed in the laboratory to make human proteins, including the tumor markers called CEA and MUC-1, that may help immune cells in the body kill tumor cells.;

CAS number : 685563-13-7;

Drug name : PANVAC-V;

NSC code : 727026;

Codes from synonyms : CDR0000589419; CDR0000560963; CDR0000589420;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
31/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.