PML Gene - CISMeF

Preferred Label : PML Gene;

NCIt synonyms : PML Nuclear Body Scaffold Gene;

NCIt related terms : PML;

CISMeF acronym : PML;

NCIt definition : This gene plays a role in tumor suppression and is involved in the regulation of p53 in response to oncogenic signal transduction.;

Details

Origin ID

C24686;

UMLS CUI

C1366903;

Automatic exact mappings (from CISMeF team)
- Acute promyelocytic leukemia, inducer of [OMIM gene]
- PML [LOINC component]
- PML nuclear body scaffold [ORDO Gene]
- Progressive multifocal leukoencephalopathy [ORDO Disease]
- Progressive multifocal leukoencephalopathy [ICD-11 Sub-sub category]
- leukemia, promyelocytic, acute [MeSH Descriptor]
- progressive multifocal leukoencephalopathy [DO Concept]
HGNC gene
- PML nuclear body scaffold [HGNC gene]
OMIM relation
- Acute promyelocytic leukemia, inducer of [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- Acute promyelocytic leukemia, inducer of [OMIM gene]
- PML [LOINC component]
- PML nuclear body scaffold [HGNC gene]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Reference Gene Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
gene_encodes_gene_product
- Protein PML [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_involved_in_molecular_abnormality
- PML Gene Rearrangement [NCIt concept]
- PML-RARA Fusion Protein Expression [NCIt concept]
- t(15;17)(q24;q21) [NCIt concept]
gene_plays_role_in_process
- Induction of Cell Senescence [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Tumor Suppression [NCIt concept]
genetic_biomarker_related_to
- PML/RARA Fusion Gene [NCIt concept]
- PML/RARA Fusion Positive [NCIt concept]
- PML/RARA Fusion Protein [NCIt concept]
- RARA/PML Fusion Gene [NCIt concept]
- t(15;17)(q24.1;q21.1)(PML/RARA) BCR2 Type Fusion Transcript [Presence] in Blood or Tissue by Molecular Genetics Method [NCIt concept]
- t(15;17)(q24.1;q21.1)(PML/RARA) BCR2 Type Fusion Transcript/Control Transcript [Number Ratio] in Blood or Tissue by Molecular Genetics Method [NCIt concept]
- t(15;17)(q24.1;q21.1)(PML/RARA) BCR2 Type Fusion Transcript/Control Transcript [Number Ratio] in Bone Marrow by Molecular Genetics Method [NCIt concept]
- t(15;17)(q24.1;q21.1)(PML/RARA) Fusion Transcript in Blood or Tissue by FISH [NCIt concept]

Keyword's position in hierarchy(ies) :

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