Interleukin-18

Preferred Label : Interleukin-18;

NCIt synonyms : Interferon-Gamma-Inducing Factor; Interferon Gamma-Inducing Factor; Interleukin-1 Gamma; IFN-gamma-Inducing Factor; IL-1g; IL-18; IGIF; Interleukin-18 Precursor; IL18 Protein; IL18; Interleukin 18 Proprotein; Interleukin 18; IL1F4; Interferon-Gamma Inducing Factor; IL-1 Gamma;

NCIt definition : Interleukin-18 (193 aa, 22 kDa) is encoded by the human IL18 gene. This protein is involved in the regulation of both natural killer cell activity and the production of interferon gamma.;

Details

Origin ID

C20520;

UMLS CUI

C3849701;

Currated CISMeF NLP mapping
- Interleukin 18 [LOINC component]
- Interleukin-18 [FMA entity]
- Interleukin-18 [MeSH Descriptor]
- Interleukin-18 [MeSH concept]
OMIM relation
- Interleukin 18 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- IL18 protein, human [MeSH concept]
- IL18 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- IL18 Gene [NCIt concept]
- Interleukin Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Cellular Anthrax Toxin Pathway [NCIt concept]
- Cytokine Network Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Cytosolic DNA-Sensing Pathway [NCIt concept]
- IL12 Signaling Pathway [NCIt concept]
- IL12/STAT4 Signaling Pathway [NCIt concept]
- IL18 Signaling Pathway [NCIt concept]
- IL23-Mediated Signaling Pathway [NCIt concept]
- IL27-Mediated Signaling Pathway [NCIt concept]
- Malaria Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- Ras-Independent Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Salmonella Pathway [NCIt concept]
- Th1/Th2 Differentiation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Immune Response Process [NCIt concept]
- Inflammatory Response [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
is_target
- Camoteskimab [NCIt concept]

Keyword's position in hierarchy(ies) :

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