Interleukin-18

Preferred Label : Interleukin-18;

MeSH definition : A cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activity of NK CELLS and CYTOTOXIC T-LYMPHOCYTES, and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity.;

MeSH synonym : il18; inducing factor, ifn-gamma; inducing factor, interferon-gamma; ifn-gamma inducing factor; il-18; ifn-gamma-inducing factor; interferon-gamma inducing factor; interferon gamma inducing factor; interferon-gamma-inducing factor; ifn gamma inducing factor; interleukin 18;

Wikipedia automatic translation : Interleukin;

MeSH annotation : DF: IL18;

Wikipedia link : https://en.wikipedia.org/wiki/Interleukin;

Is substance : O;

Details

Origin ID

D020382;

UMLS CUI

C0383327;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Iboctadekin [NCIt concept]
- Interleukin 18 [LOINC component]
- Interleukin-18 [FMA entity]
- Interleukin-18 [NCIt concept]
Indexing information
- interleukin-18 binding protein [MeSH Supplementary Concept]
Record concept(s)
- Interleukin-18 [MeSH concept]
Related MeSH Supplementary Concept(s)
- EGF-IL-18 fusion protein, mouse [MeSH Supplementary Concept]
- IL18 protein, human [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Interleukin 18 [LOINC component]
- Interleukin 18 (substance) [SNOMED CT concept]
- Interleukin-18 [FMA entity]

Keyword's position in hierarchy(ies) :

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