NCIt synonyms : Interleukin-18; IFN-Gamma-Inducing Factor; Interferon-Gamma-Inducing Factor; IL-18; Therapeutic Interleukin-18; Human Recombinant Interleukin-18; Recombinant Interleukin-18; Human Interleukin-18 (Recombinant, Expressed in Escherichia coli);
NCIt definition : A recombinant therapeutic agent which is chemically identical to or similar to the
endogenous cytokine interleukin-18 (IL-18). Produced primarily by macrophages, IL-18
induces the production of interferon-gamma (IFN-gamma), and enhances the activity
of natural killer (NK) and cytotoxic T lymphocytes (CTL). As a potential immunotherapeutic
agent, iboctadekin displays antitumor effects in vitro and in animal models. (NCI04);
Currated CISMeF NLP mapping