26S Proteasome Non-ATPase Regulatory Subunit 3

Preferred Label : 26S Proteasome Non-ATPase Regulatory Subunit 3;

NCIt synonyms : 26S Proteasome Regulatory Subunit S3; Proteasome Subunit p58; 26S Proteasome Regulatory Subunit RPN3; p58; PSMD3; Tissue Specific Transplantation Antigen 2;

NCIt definition : 26S proteasome non-ATPase regulatory subunit 3 (534 aa, 61 kDa) is encoded by the human PSMD3 gene. This protein plays a role in the regulation of 26S proteasome-mediated, ubiquitin-dependent protein catabolism.;

Details

Origin ID

C188910;

UMLS CUI

C2932690;

Automatic exact mappings (from CISMeF team)
- Cyclin-dependent kinase 11b [OMIM gene]
- Proteasome 26s subunit, non-atpase, 3 [OMIM gene]
OMIM relation
- Proteasome 26s subunit, non-atpase, 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- proteasome activator PA700 subunit p58, human [MeSH Supplementary Concept]
- proteasome activator PA700 subunit p58, human [MeSH concept]
gene_encodes_gene_product
- PSMD3 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
- Nucleus [NCIt concept]
- PA700 Regulatory Module [NCIt concept]
gene_product_is_element_in_pathway
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- Amyotrophic Lateral Sclerosis Pathway [NCIt concept]
- Huntington's Disease Pathway [NCIt concept]
- Parkinson's Disease Pathway KEGG [NCIt concept]
- Prion Disease Pathway [NCIt concept]
- Proteasome Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Polyubiquitination [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]

Keyword's position in hierarchy(ies) :

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