Replication Factor C Subunit 2

Preferred Label : Replication Factor C Subunit 2;

NCIt synonyms : A1 40 kDa Subunit; RFC 40 kDa Subunit; Activator 1 Subunit 2; RF-C 40 kDa Subunit; Activator 1 40 kDa Subunit; Replication Factor C 40 kDa Subunit; RFC2; RFC40;

NCIt definition : Replication factor C subunit 2 (354 aa, 39 kDa) is encoded by the human RFC2 gene. This protein plays a role in DNA replication and elongation.;

NCIt note : Replication factor C subunit 2 is a subunit for replication factor C (RFC; activator 1). RFC is comprised of five distinct subunits. RFC2 forms a core complex with RFC4 and RFC5. This core complex possesses proliferating cell nuclear antigen (PNCA)-stimulated DNA-dependent ATPase activity. (EntrezGene);

Details

Origin ID

C180776;

UMLS CUI

C1566647;

Automatic exact mappings (from CISMeF team)
- Replication factor C, subunit 2 [OMIM gene]
- replication factor C subunit 2 [ORDO Gene]
- replication factor C subunit 2 [HGNC gene]
- replication protein c [MeSH Descriptor]
OMIM relation
- Replication factor C, subunit 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- RFC2 protein, human [MeSH Supplementary Concept]
- RFC2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Cycle Gene [NCIt concept]
- RFC2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
- Regulatory Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- ATPase Domain [NCIt concept]
gene_product_is_element_in_pathway
- DNA Replication Pathway [NCIt concept]
- Mismatch Repair Pathway [NCIt concept]
- Nucleotide Excision Repair Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- ATP Hydrolysis [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- DNA Replication [NCIt concept]
- Nucleotide Excision Repair [NCIt concept]
- Telomere Maintenance [NCIt concept]

Keyword's position in hierarchy(ies) :

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