Replication Factor C Subunit 5

Preferred Label : Replication Factor C Subunit 5;

NCIt synonyms : RFC36; Activator 1 Subunit 5; A1 36 kDa Subunit; RFC 36 kDa Subunit; RF-C 36 kDa Subunit; RFC5; Replication Factor C 36 kDa Subunit; Activator 1 36 kDa Subunit;

NCIt definition : Replication factor C subunit 5 (340 aa, 38 kDa) is encoded by the human RFC5 gene. This protein is involved in ATP-dependent elongation of replicating DNA.;

NCIt note : Replication factor C subunit 5 is a subunit for replication factor C (RFC; activator 1). RFC is comprised of five distinct subunits. RFC5 forms a core complex with RFC2 and RFC4. This core complex possesses proliferating cell nuclear antigen (PNCA)-stimulated DNA-dependent ATPase activity. (EntrezGene);

Details

Origin ID

C180753;

UMLS CUI

C1566650;

Automatic exact mappings (from CISMeF team)
- Replication factor C, subunit 5 [OMIM gene]
- replication factor C subunit 5 [HGNC gene]
- replication protein c [MeSH Descriptor]
OMIM relation
- Replication factor C, subunit 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- RFC5 protein, human [MeSH Supplementary Concept]
- RFC5 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Cycle Gene [NCIt concept]
- RFC5 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
- Regulatory Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- ATPase Domain [NCIt concept]
gene_product_is_element_in_pathway
- DNA Replication Pathway [NCIt concept]
- Mismatch Repair Pathway [NCIt concept]
- Nucleotide Excision Repair Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- ATP Hydrolysis [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- DNA Replication [NCIt concept]
- Nucleotide Excision Repair [NCIt concept]
- Telomere Maintenance [NCIt concept]

Keyword's position in hierarchy(ies) :

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