Rho Guanine Nucleotide Exchange Factor 5

Preferred Label : Rho Guanine Nucleotide Exchange Factor 5;

NCIt synonyms : Ephexin-3; TIM; ARHGEF5; Rho Guanine Nucleotide Exchange Factor-5; GEF5; TIM1; Guanine Nucleotide Regulatory Protein TIM;

NCIt definition : Rho guanine nucleotide exchange factor 5 (1597 aa, 177 kDa) is encoded by the human ARHGEF5 gene. This protein plays a role in the activation of Rho family GTPases.;

Details

Origin ID

C17976;

UMLS CUI

C3711667;

OMIM relation
- Rho guanine nucleotide exchange factor 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ARHGEF5 protein, human [MeSH Supplementary Concept]
- ARHGEF5 protein, human [MeSH concept]
gene_encodes_gene_product
- ARHGEF5 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- DH Domain [NCIt concept]
- PH Domain [NCIt concept]
- SH3 Domain [NCIt concept]
gene_product_is_element_in_pathway
- Rho Cell Motility Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Post-Translational Modification [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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