HLA-E wt Allele

Preferred Label : HLA-E wt Allele;

NCIt synonyms : MHC Class Ib Antigen Gene; QA1, Mouse, Homolog of Gene; Major Histocompatibility Complex, Class I, E wt Allele; QA1; HLAE; HLA-E Histocompatibility Type Gene; HLA-6.2;

NCIt definition : Human HLA-E wild-type allele is located in the vicinity of 6p22.1 and is approximately 5 kb in length. This allele, which encodes HLA class I histocompatibility antigen, alpha chain E protein, plays a role in the modulation of natural killer cell cytotoxicity.;

NCI Metathesaurus CUI : CL1662400;

GenBank Accession Number : M20022;

Details

Origin ID

C179683;

UMLS CUI

C5551114;

Automatic exact mappings (from CISMeF team)
- Major histocompatibility complex, class I, e [OMIM gene]
OMIM relation
- Major histocompatibility complex, class I, e [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 6p21.1 [NCIt concept]
gene_is_element_in_pathway
- Adherens Junction Formation Pathway [NCIt concept]
- Allograft Rejection Pathway [NCIt concept]
- Antigen Processing and Presentation Pathway [NCIt concept]
- Autoimmune Thyroid Disease Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Graft-Versus-Host Disease Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Type I Diabetes Mellitus Pathway [NCIt concept]
- Viral Myocarditis Pathway [NCIt concept]
gene_plays_role_in_process
- Antigen Presentation [NCIt concept]
- Cell-Mediated Cytotoxicity [NCIt concept]
- Immune System Process [NCIt concept]
- Immunologic Tolerance [NCIt concept]
- Immunoregulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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