" /> Von Hippel-Lindau Disease Tumor Suppressor - CISMeF





Preferred Label : Von Hippel-Lindau Disease Tumor Suppressor;

NCIt synonyms : VHL Protein; von Hippel Lindau Tumor Suppressor Protein; pVHL; G7 Protein; Elongin Binding Protein; Protein G7; VHL;

NCIt definition : Von Hippel-Lindau disease tumor suppressor (213 aa, 24 kDa) is encoded by the human VHL gene. This protein plays a role in protein ubiquitination and regulation of protein degradation.;

NCIt note : Von Hippel-Lindau disease tumor suppressor forms a complex with Elongin B-C and cullin-2. This complex is involved in the E3 ubiquitination and degradation of proteins including the HIF-1 transcription factor complex.;

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29/07/2025


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