T-Cell Surface Glycoprotein CD8 Beta Chain

Preferred Label : T-Cell Surface Glycoprotein CD8 Beta Chain;

NCIt synonyms : CD8B; LYT3; CD8b Antigen; CD8B1; T-Cell Glycoprotein CD8b; CD8 Antigen Beta Polypeptide-1;

NCIt definition : T-cell surface glycoprotein CD8 beta chain (210 aa, 24 kDa) is encoded by the human CD8B gene. This protein plays a role in T-cell cytotoxicity.;

Details

Origin ID

C17441;

UMLS CUI

C1332717;

OMIM relation
- Cd8 antigen, beta polypeptide [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CD8B Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
gene_product_expressed_in_tissue
- T-Lymphocyte [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Immunoglobulin Family Protein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like V-Type Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Antigen Processing and Presentation Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Downstream Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- IL12-Mediated Signaling Pathway [NCIt concept]
- Primary Immunodeficiency Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
gene_product_is_physical_part_of
- T-Cell Surface Glycoprotein CD8 [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune System Process [NCIt concept]
- Signal Transduction [NCIt concept]
- T-Cell Activation [NCIt concept]
is_target
- Anti-CD8b Antibody/IL-2 Mutein Fusion Protein AB248 [NCIt concept]

Keyword's position in hierarchy(ies) :

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