T-Cell Surface Glycoprotein CD8

Preferred Label : T-Cell Surface Glycoprotein CD8;

NCIt synonyms : CD8 Co-Receptor; CD8; CD8 Antigen; CD8 Complex;

NCIt definition : A dimeric protein complex that functions as a co-receptor for the T-cell receptor and is involved with both signal transduction in and antigen interactions with T-lymphocytes. CD8 is commonly composed of a heterodimer of the T-cell surface glycoprotein CD8 alpha and beta chains, but functional homodimers of the alpha chain also exist.;

Details

Origin ID

C139799;

UMLS CUI

C0085358;

Automatic exact mappings (from CISMeF team)
- CD8 [LOINC component]
- CD8 Ag [LOINC component]
- CD8 Antigens [MeSH concept]
- CD8 Antigens [MeSH Descriptor]
- CD8 cells [LOINC component]
- CD8a molecule [ORDO Gene]
- Cd8 antigen, alpha polypeptide [OMIM gene]
Semantic type(s)
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- CD8 [LOINC component]
- CD8 Ag [LOINC component]
- CD8 Antigens [MeSH Descriptor]
- CD8 Antigens [MeSH concept]
- Lymphocyte antigen CD8 (substance) [SNOMED CT concept]
- lymphocyte antigen cd8 [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_associated_anatomy
- T-Lymphocyte and Natural Killer Cell [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Binding [NCIt concept]
- Signal Transduction [NCIt concept]
has_gene_product_element
- T-Cell Surface Glycoprotein CD8 Alpha Chain [NCIt concept]
- T-Cell Surface Glycoprotein CD8 Beta Chain [NCIt concept]
is_target
- Zirconium Zr 89 Crefmirlimab Berdoxam [NCIt concept]

Keyword's position in hierarchy(ies) :

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