DNA Excision Repair Protein ERCC-8

Preferred Label : DNA Excision Repair Protein ERCC-8;

NCIt synonyms : Cockayne Syndrome WD Repeat Protein CSA; Excision Repair Cross-Complementation Group 8; Cockayne Syndrome WD-Repeat Protein CSA; ERCC8;

NCIt definition : DNA excision repair protein ERCC-8 (396 aa, 44 kDa) is encoded by the human ERCC8 gene. This protein plays a role in promoting the ubiquitination of DNA excision repair protein ERCC6 in a UV-dependent manner.;

Details

Origin ID

C173247;

UMLS CUI

C5400780;

Automatic exact mappings (from CISMeF team)
- ERCC excision repair 8, CSA ubiquitin ligase complex subunit [ORDO Gene]
- Ercc excision repair 8, csa ubiquitin ligase complex subunit [OMIM gene]
OMIM relation
- Ercc excision repair 8, csa ubiquitin ligase complex subunit [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- ERCC8 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_structural_domain_or_motif
- WD Repeat [NCIt concept]
gene_product_is_element_in_pathway
- Nucleotide Excision Repair Pathway [NCIt concept]
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Repair [NCIt concept]
- Nucleotide Excision Repair [NCIt concept]
- Ubiquitination [NCIt concept]

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