SH3 and Multiple Ankyrin Repeat Domains Protein 2

Preferred Label : SH3 and Multiple Ankyrin Repeat Domains Protein 2;

NCIt synonyms : Cortactin-Binding Protein 1; Proline-Rich Synapse-Associated Protein 1; Cortactin SH3 Domain-Binding Protein; Cortactin Binding Protein 1; GKAP/SAPAP Interacting Protein; Proline-Rich Synapse Associated Protein 1; SHANK2;

NCIt definition : SH3 and multiple ankyrin repeat domains protein 2 (1470 aa, 159 kDa) is encoded by the human SHANK2 gene. This protein is involved in organization of both the structure and function of the synaptic junction.;

Details

Origin ID

C147944;

UMLS CUI

C1438514;

Automatic exact mappings (from CISMeF team)
- Sh3 and multiple ankyrin repeat domains 2 [OMIM gene]
OMIM relation
- Sh3 and multiple ankyrin repeat domains 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SHANK2 protein, human [MeSH Supplementary Concept]
- SHANK2 protein, human [MeSH concept]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- SHANK2 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Chemical Synapse [NCIt concept]
- Plasma Membrane [NCIt concept]
- Postsynaptic Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- PDZ Domain [NCIt concept]
- Proline-Rich Domain [NCIt concept]
- SAM Domain [NCIt concept]
- SH3 Domain [NCIt concept]
- SH3-Binding Motif [NCIt concept]
gene_product_plays_role_in_biological_process
- Learning [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients