BRCT Domain - CISMeF

Preferred Label : BRCT Domain;

NCIt synonyms : Breast Cancer Carboxy-Terminal Domain;

NCIt definition : BRCT domain was first identified in C-terminal domain of breast cancer associated protein and was found in many proteins that regulate the cellular response to DNA repair, where these domains act as multi-purpose protein-protein interaction modules. Crystallography study reveals that two 95 amino acid BRCT repeats within the domain adopt similar structures that pack together in a head-to-tail arrangement. (NCI);

Details

Origin ID

C14042;

UMLS CUI

C1511026;

Semantic type(s)
- Amino Acid Sequence [UMLS semantic type]
is_structural_domain_or_motif_of_gene_product
- BRCA1-Associated RING Domain Protein 1 [NCIt concept]
- Breast Cancer Type 1 Susceptibility Protein [NCIt concept]
- DNA Ligase 4 [NCIt concept]
- DNA Repair Protein XRCC1 [NCIt concept]
- DNA Topoisomerase 2-Binding Protein 1 [NCIt concept]
- Mediator of DNA Damage Checkpoint Protein 1 [NCIt concept]
- Microcephalin [NCIt concept]
- Nibrin [NCIt concept]
- PAX-Interacting Protein 1 [NCIt concept]
- Poly [ADP-Ribose] Polymerase 1 [NCIt concept]
- Protein ECT2 [NCIt concept]
- Replication Factor C Subunit 1 [NCIt concept]
- Telomeric Repeat-Binding Factor 2-Interacting Protein 1 [NCIt concept]

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