Mediator of DNA Damage Checkpoint Protein 1

Preferred Label : Mediator of DNA Damage Checkpoint Protein 1;

NCIt synonyms : Nuclear Factor with BRCT Domains 1; Homolog to Drosophila Photoreceptor Protein Calphotin; Mediator of DNA Damage Checkpoint 1; MDC1;

NCIt definition : Mediator of DNA damage checkpoint protein 1 (2089 aa, 227 kDa) is encoded by the human MDC1 gene. This protein plays a role in checkpoint mediated cell cycle arrest.;

Details

Origin ID

C104644;

UMLS CUI

C3537382;

OMIM relation
- Mediator of dna damage checkpoint protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Cycle Gene [NCIt concept]
- MDC1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Regulatory Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- BRCT Domain [NCIt concept]
- FHA Domain [NCIt concept]
- Nuclear Localization Signal [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Checkpoint [NCIt concept]
- Cell Cycle Progression [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- G2 to M Transition Process [NCIt concept]
- S Phase Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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