Menogaril - CISMeF

Preferred Label : Menogaril;

NCIt synonyms : 7-con-O-methylnorgarol; 7-con-O-methylnogarol; TUT-7; MEN; 7-(R)-O-methylnogarol; 7-OMEN; [2R-(2alpha,3beta,4alpha,5beta,6alpha,11alpha,13alpha)]-4-(dimethylamino)-3,4,5,6,11,12,13,14-octahydro-3,5,8,10,13-pentahydroxy-11-methoxy-6,13-dimethyl-2,6-epoxy-2H-naphthaceno[1,2-b]oxocin-9,16-dione;

NCIt related terms : OMEN,7-; 7(R)-O-Methylnogarol; U-52047;

NCIt definition : A semisynthetic derivative of the anthracycline antineoplastic antibiotic nogalamycin. Menogaril intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin. (NCI04);

UNII : 8JSV4O30HQ;

InChIKey : LWYJUZBXGAFFLP-AOZXJLOUSA-N;

CAS number : 71628-96-1;

Drug name : Menogarol;

Molecule name : U-52047;

Chemical formula : C28H31NO10;

NSC code : 269148;

Codes from synonyms : NSC0269148;

Details

Origin ID

C1389;

UMLS CUI

C0127527;

Currated CISMeF NLP mapping
- TUT-7 [MeSH concept]
- menogaril [MeSH Descriptor]
- menogaril [MeSH concept]
False automatic mappings
- Man (person) [SNOMED CT concept]
- Multiple endocrine neoplasia [ORDO Disease]
- men [MedlinePlus Group]
- men [MeSH Descriptor]
- men [MeSH concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- menogaril [MeSH concept]
- menogaril [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Cyclophosphamide/Fluorouracil/Menogaril [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients