Oncogene TIM Protein

Preferred Label : Oncogene TIM Protein;

NCIt synonyms : Rho Guanine Nucleotide Exchange Factor 5 Isoform 2; Oncoprotein TIM; TIM; TIM1; p60 TIM; Transforming Immortalized Mammary Oncogene Protein; Transforming Immortalized Mammary Protein; Rho Guanine Nucleotide Exchange Factor 5 p60 Isoform; p60;

NCIt definition : Oncogene TIM protein (519 aa, 60 kDa) is encoded by the human ARHGEF5 gene. This protein is involved in the activation of Rho family small GTPases and may induce cellular transformation.;

Details

Origin ID

C132338;

UMLS CUI

C4319633;

Automatic exact mappings (from CISMeF team)
- Hepatitis a virus cellular receptor 1 [OMIM gene]
- Rho guanine nucleotide exchange factor 5 [OMIM gene]
- Timeless circadian regulator [OMIM gene]
- sequestosome 1 [ORDO Gene]
OMIM relation
- Rho guanine nucleotide exchange factor 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- ARHGEF5 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- DH Domain [NCIt concept]
- PH Domain [NCIt concept]
- SH3 Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Post-Translational Modification [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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