" /> Endothelin-1 - CISMeF





Preferred Label : Endothelin-1;

NCIt synonyms : EDN1; Endothelin 1; ET-1; Preproendothelin-1; PPET1; Preproendothelin 1;

NCIt definition : Endothelin-1 (212 aa, 24 kDa) is encoded by the human EDN1 gene. This protein is involved in vasoconstriction.;

NCIt note : Endothelin-1 is proteolytically processed to form big endothelin-1 (38 amino acids) or a 21 amino acid peptide also called endothelin-1. The active forms inhibits active Na-K transport by inhibiting Na( )-K( )-ATPase in intact renaltubular epithelial cells.;

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31/07/2025


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