Platelet-Derived Growth Factor D

Preferred Label : Platelet-Derived Growth Factor D;

NCIt synonyms : Spinal Cord Derived Growth Factor B; Iris-Expressed Growth Factor; Spinal Cord-Derived Growth Factor-B; SCDGF-B; PDGF-D; Spinal Cord-Derived Growth Factor B;

NCIt definition : Platelet-derived growth factor D (370 aa, 43 kDa) is encoded by the human PDGFD gene. This protein is involved in growth factor signaling that modulates many developmental and cellular processes.;

NCIt note : Proteolytic removal of the N-terminal CUB domain of platelet-derived growth factor D releases the core domain and is required for receptor binding. (UniProt);

Details

Origin ID

C124880;

UMLS CUI

C1447990;

Automatic exact mappings (from CISMeF team)
- Platelet-derived growth factor D [OMIM gene]
- platelet derived growth factor D [HGNC gene]
OMIM relation
- Platelet-derived growth factor D [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PDGFD protein, human [MeSH Supplementary Concept]
- PDGFD protein, human [MeSH concept]
gene_encodes_gene_product
- Growth Factor Gene [NCIt concept]
- PDGFD Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Platelet-Derived Growth Factor [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Gap Junction Assembly Pathway [NCIt concept]
- Melanoma Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Developmental Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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