Melanoma-Associated Antigen 4

Preferred Label : Melanoma-Associated Antigen 4;

NCIt synonyms : MAGE-41 Antigen; Cancer/Testis Antigen 1.4; MAGE-X2 Antigen; Cancer/Testis Antigen Family 1, Member 4; MAGE-4 Antigen; MAGE-A4; MAGEA4;

NCIt definition : Melanoma-associated antigen 4 (317 aa, 35 kDa) is encoded by the human MAGEA4 gene. This protein may be involved in embryonal development, tumor transformation, or tumor progression.;

Details

Origin ID

C104515;

UMLS CUI

C3537350;

Automatic exact mappings (from CISMeF team)
- MAGE family member A4 [HGNC gene]
OMIM relation
- Melanoma antigen, family a, 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cancer Gene [NCIt concept]
- MAGEA4 Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Metastasis Induction [NCIt concept]
- Tumorigenesis [NCIt concept]
is_target
- Afamitresgene Autoleucel [NCIt concept]
- Anti-HLA-A2-MAGE-A4/Anti-CD3 Bispecific Antibody RO7444973 [NCIt concept]
- Anti-MAGE-A4 T-cell Receptor/Anti-CD3 scFv Fusion Protein IMC-C103C [NCIt concept]
- MAGE-A4-specific T-cell Engager CDR404 [NCIt concept]
- MAGE-A4-specific TCR Gene-transduced Autologous T Lymphocytes TBI-1201 [NCIt concept]
- NY-ESO-1/MAGE-A4/PRAME/Survivin/SSX2-specific Autologous Cytotoxic T Lymphocytes [NCIt concept]
- Uzatresgene Autoleucel [NCIt concept]

Keyword's position in hierarchy(ies) :

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