Forkhead Box Protein P3

Preferred Label : Forkhead Box Protein P3;

NCIt synonyms : FOXP3delta7; Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked; Scurfin; FOXP3;

NCIt definition : Forkhead box protein P3 (431 aa, 47 kDa) is encoded by the human FOXP3 gene. This protein is involved in transcription regulation and the immune response.;

NCIt note : Multiple isoforms of forkhead box protein P3 are generated through alternate splicing.;

Details

Origin ID

C104396;

UMLS CUI

C1504797;

Automatic exact mappings (from CISMeF team)
- FOXP3 [LOINC component]
- Forkhead box p3 [OMIM gene]
- Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome [ORDO Disease]
- X-linked immune dysregulation – polyendocrinopathy – enteropathy [ICD-11 More detail]
- forkhead box P3 [ORDO Gene]
OMIM relation
- Forkhead box p3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- FOXP3 [LOINC component]
- FOXP3 protein, human [MeSH Supplementary Concept]
- FOXP3 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- FOXP3 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2H2 Zinc Finger [NCIt concept]
- Forkhead Box [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- T-Cell Differentiation [NCIt concept]
- Transcriptional Regulation [NCIt concept]
is_target
- Anti-FOXP3 Antisense Oligonucleotide AZD8701 [NCIt concept]

Keyword's position in hierarchy(ies) :

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