Preferred Label : tocilizumab;
MeSH note : anti-IL-6 receptor antibody for treatment of rheumatoid arthritis, Crohn's disease
& Castleman disease;
CISMeF synonym : actemra; chugai brand of tocilizumab;
MeSH synonym : atlizumab; monoclonal antibody, MRA;
MeSH hyponym : R-1569; MSB-11456; BAT1806; Roactemra;
Is substance : O;
UNII : I031V2H011;
Origin ID : C502936;
UMLS CUI : C1609165;
ATC code(s)
- CISMeF manual mappings
- Exact mapping(s) to DCI
- MeSH term(s) associated for indexing
- Record concept(s)
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
https://ansm.sante.fr/tableau-marr/tocilizumab-1
2024
false
false
false
France
French
risk management
tocilizumab
infusions, intravenous
injections, subcutaneous
guidelines for drug use
tocilizumab
tocilizumab
patient education handout
continuity of patient care
tocilizumab
---
https://www.ema.europa.eu/en/medicines/human/EPAR/tyenne
2024
false
false
false
Netherlands
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
tocilizumab
tocilizumab
tocilizumab
biosimilar pharmaceuticals
---
https://ansm.sante.fr/tableau-marr/tocilizumab
2022
false
false
false
France
French
risk management
guidelines for drug use
patients guideline
continuity of patient care
patient education handout
tocilizumab
tocilizumab
tocilizumab
tocilizumab
injections, subcutaneous
infusions, intravenous
receptors, interleukin-6
interleukin 6 receptor inhibitor
self administration
---
https://www.has-sante.fr/jcms/p_3318928/fr/roactemra-tocilizumab-covid-19
2022
false
false
false
France
evaluation of the transparency committee
COVID-19
adult
oxygen inhalation therapy
glucocorticoids
infusions, intravenous
treatment outcome
drug therapy, combination
tocilizumab
tocilizumab
---
https://www.usherbrooke.ca/baladocritique/archives/episode-41-etude-recovery-volet-tocilizumab
2021
Canada
COVID-19
sound
tocilizumab
tocilizumab
data collection
tocilizumab
episode of
---
https://www.has-sante.fr/jcms/p_3295750/fr/roactemra-tocilizumab
2021
France
evaluation of the transparency committee
tocilizumab
resulting in
registries
outcome studies
tocilizumab
tocilizumab
Roactemra
Outcome Assessment, Health Care
---
https://www.cochrane.org/fr/CD013484/EYES_quels-sont-les-benefices-et-les-risques-du-tocilizumab-un-medicament-qui-reduit-linflammation-dans
2021
United Kingdom
review of literature
french abstract
tocilizumab
risk assessment
Diseases
risks and benefits
tocilizumab
disease, nos
Arteritis
drug, nos
Blood vessel
giant cell arteritis
pharmaceutical preparations
Cell
inflammation
Inflammation
inflammation, nos
blood vessels
disease
Inflammation
giant cell arteritis
celiac disease
tocilizumab
---
https://presse.inserm.fr/confirmation-des-resultats-prometteurs-de-lessai-corimuno-toci-1-montrant-une-amelioration-de-la-survie-des-patients-atteints-de-pneumonie-covid-19-moderee-a-severe/43399
2021
false
false
false
France
French
journal article
COVID-19
clinical trials as topic
treatment outcome
tocilizumab
survival
antibodies, monoclonal, humanized
---
https://www.has-sante.fr/jcms/p_3262250/fr/roactemra-tocilizumab
2021
false
false
false
France
treatment outcome
insurance, health, reimbursement
tocilizumab
child
Cytokine Release Syndrome
syndrome
cytotoxicity, immunologic
cytokines
adolescent
adult
Chimeric antigen receptor T-cell therapy
Cytokine Release Syndrome
Chimeric Antigen Receptor T-cells
infusions, intravenous
Receptors, Chimeric Antigen
t-lymphocytes
evaluation of the transparency committee
tocilizumab
antibodies, monoclonal, humanized
---
https://www.hcsp.fr/explore.cgi/avisrapportsdomaine?clefr=997
2021
France
coronavirus infections
pneumonia, viral
practice guideline
Monoclonal antibodies
health planning guidelines
therapeutics
monoclonal antibody
tocilizumab
Monoclonal antibodies
antibodies, monoclonal
Treatments
tocilizumab
Treatments
therapeutics
antibodies, monoclonal, humanized
pandemics
COVID-19
---
https://www.inesss.qc.ca/fileadmin/doc/INESSS/COVID-19/Outil_clinique_Usage-Tocilizumab-Sarilumab.pdf
2021
false
false
true
Canada
French
Interleukin-6
quebec
tocilizumab
tocilizumab
sarilumab
sarilumab
treatment outcome
drug therapy, combination
glucocorticoids
adult
aged
Interleukin 6 receptor antagonist (disposition)
guidelines for drug use
receptors, interleukin-6
biological therapy
pneumonia, viral
coronavirus infections
antibodies, monoclonal, humanized
pandemics
COVID-19
---
https://www.has-sante.fr/jcms/p_3193723/fr/roactemra
2020
false
false
false
France
insurance, health, reimbursement
treatment outcome
tocilizumab
tocilizumab
adolescent
rheumatoid arthritis, systemic juvenile
Polyarticular juvenile idiopathic arthritis
arthritis, juvenile
evaluation of the transparency committee
antibodies, monoclonal, humanized
---
https://www.inesss.qc.ca/fileadmin/doc/INESSS/COVID-19/COVID-19_INESSS_biotherapie_IL-1.pdf
2020
false
false
true
Canada
pneumonia, viral
coronavirus infections
Interleukin-6
quebec
siltuximab
siltuximab
tocilizumab
tocilizumab
sarilumab
sarilumab
treatment outcome
guideline
receptors, interleukin-6
biological therapy
interleukin-6
pneumonia, viral
coronavirus infections
pandemics
antibodies, monoclonal
antibodies, monoclonal, humanized
COVID-19
---
http://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2019/69991a-fra.php
2019
false
false
false
France
French
pharmacovigilance note
risk
tocilizumab
tocilizumab
guidelines for drug use
Chemical and Drug Induced Liver Injury
arthritis, juvenile
arthritis, rheumatoid
giant cell arteritis
infusions, intravenous
injections, subcutaneous
continuity of patient care
liver function tests
antibodies, monoclonal, humanized
---
https://www.has-sante.fr/portail/jcms/c_2964632/fr/roactemra
2019
false
false
false
France
French
infant
tocilizumab
tocilizumab
rheumatoid arthritis, systemic juvenile
treatment outcome
insurance, health, reimbursement
evaluation of the transparency committee
antibodies, monoclonal, humanized
arthritis, juvenile
---
https://ansm.sante.fr/informations-de-securite/roactemra-r-tocilizumab-risque-rare-datteintes-hepatiques-graves-y-compris-dinsuffisance-hepatique-aigue-necessitant-une-greffe
2019
false
false
false
France
French
pharmacovigilance note
Chemical and Drug Induced Liver Injury
tocilizumab
tocilizumab
continuity of patient care
Chemical and Drug Induced Liver Injury
transaminases
antibodies, monoclonal, humanized
---
https://www.cochrane.org/fr/CD012984/tocilizumab-pour-la-maladie-oculaire-thyroidienne
2018
false
false
false
France
United Kingdom
review of literature
french abstract
eye diseases
Disease
thyroid diseases
eye, nos
disease, nos
tocilizumab
Diseases of the eye
tocilizumab
disease
Diseases
disease
antibodies, monoclonal, humanized
---
https://www.has-sante.fr/portail/jcms/c_2897001/en/roactemra
https://www.has-sante.fr/portail/jcms/c_2897001/fr/roactemra-tocilizumab-immunosuppresseur
2018
false
false
false
France
adult
adolescent
child
tocilizumab
infusions, intravenous
tocilizumab
Cytokine Release Syndrome
treatment outcome
guidelines for drug use
evaluation of the transparency committee
antibodies, monoclonal, humanized
---
https://www.has-sante.fr/portail/jcms/c_2879351/fr/roactemra
2018
false
false
false
France
child
injections, subcutaneous
tocilizumab
treatment outcome
tocilizumab
arthritis, juvenile
drug therapy, combination
evaluation of the transparency committee
antibodies, monoclonal, humanized
---
https://www.has-sante.fr/portail/jcms/c_2872820/fr/roactemra
2018
false
false
false
false
France
French
evaluation of the transparency committee
tocilizumab
tocilizumab
injections, subcutaneous
drug therapy, combination
glucocorticoids
giant cell arteritis
treatment outcome
antibodies, monoclonal, humanized
---
http://www.cri-net.com/fiches-pratiques-et-recommandations/prise-en-charge-pratique-des-patients-sous-tocilizumab
2017
false
false
false
France
French
guidelines for drug use
arthritis, rheumatoid
tocilizumab
tocilizumab
tocilizumab
receptors, interleukin-6
adult
child
infusions, intravenous
injections, subcutaneous
pregnancy
continuity of patient care
vaccination
arthritis, juvenile
Castleman Disease
spondylarthropathies
polymyalgia rheumatica
giant cell arteritis
Off-Label use
patient care management
practice guideline
consensus
patients guideline
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized
---
http://www.has-sante.fr/portail/jcms/c_2628638/fr/roactemra-sc
2016
false
true
false
France
French
evaluation of the transparency committee
tocilizumab
tocilizumab
tocilizumab
injections, subcutaneous
receptors, interleukin-6
drug therapy, combination
methotrexate
adult
arthritis, rheumatoid
treatment outcome
insurance, health, reimbursement
aged
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized
---
http://www.has-sante.fr/portail/jcms/c_2635028/fr/roactemra-polyarthrite-rhumatoide
2016
false
true
false
France
French
evaluation of the transparency committee
tocilizumab
tocilizumab
tocilizumab
receptors, interleukin-6
drug therapy, combination
methotrexate
adult
arthritis, rheumatoid
treatment outcome
insurance, health, reimbursement
aged
infusions, intravenous
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized
---
http://www.has-sante.fr/portail/jcms/c_2635025/fr/roactemra-arthrite-juvenile-idiopathique-systemique
2016
false
France
French
evaluation of the transparency committee
rheumatoid arthritis, systemic juvenile
tocilizumab
tocilizumab
tocilizumab
arthritis, juvenile
child
treatment outcome
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized
infusions, intravenous
drug therapy, combination
---
Intérêt clinique insuffisant dans le traitement de la polyarthrite rhumatoïde chez
les adultes non précédemment traités par méthotrexate.
http://www.has-sante.fr/portail/jcms/c_2585423/fr/roactemra
http://www.has-sante.fr/portail/jcms/c_2585423/fr/roactemra-tocilizumab-inhibiteur-des-recepteurs-de-l-interleukine-6
2015
false
true
false
France
French
evaluation of the transparency committee
guidelines for drug use
tocilizumab
tocilizumab
tocilizumab
injections, subcutaneous
receptors, interleukin-6
methotrexate
adult
arthritis, rheumatoid
treatment outcome
insurance, health, reimbursement
aged
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized
---
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=69107620
2015
false
false
false
France
French
summary of product characteristics
tocilizumab
package leaflet
evaluation of the transparency committee
antibodies, monoclonal, humanized
---
http://www.has-sante.fr/portail/jcms/c_1759071/fr/roactemra
2014
false
France
French
drug therapy, combination
methotrexate
Juvenile idiopathic arthritis, extended oligoarthritis (disorder)
guidelines for drug use
evaluation of the transparency committee
tocilizumab
tocilizumab
tocilizumab
infusions, intravenous
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized
arthritis, juvenile
child
adolescent
treatment outcome
---
http://www.has-sante.fr/portail/jcms/c_1758974/fr/roactemra
2014
false
false
false
France
French
evaluation of the transparency committee
guidelines for drug use
tocilizumab
tocilizumab
tocilizumab
injections, subcutaneous
receptors, interleukin-6
drug therapy, combination
methotrexate
adult
arthritis, rheumatoid
treatment outcome
insurance, health, reimbursement
aged
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized
---
http://www.has-sante.fr/portail/jcms/c_854116/roactemra
http://www.has-sante.fr/portail/jcms/c_1717939/fr/roactemra
http://www.has-sante.fr/portail/jcms/c_1719749/fr/roactemra04122013avisct12918
2013
false
France
French
guidelines for drug use
evaluation of the transparency committee
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized
tocilizumab
infusions, intravenous
arthritis, rheumatoid
receptors, interleukin-6
tocilizumab
recombinant proteins
adult
aged
treatment outcome
tocilizumab
drug therapy, combination
---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2012-05/roactemra_09052012_avis_ct-11877.pdf
http://www.has-sante.fr/portail/jcms/c_1250135/roactemra
2012
France
French
evaluation of the transparency committee
corticosteroid therapy
tocilizumab
tocilizumab
tocilizumab
infusions, intravenous
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized
arthritis, juvenile
child
adolescent
insurance, health, reimbursement
treatment outcome
randomized controlled trials as topic
clinical trials, phase iii as topic
risk management
---
http://www.has-sante.fr/portail/jcms/c_1294163/roactemra-tocilizumab-inhibiteur-de-linterleukine-6
http://www.has-sante.fr/portail/jcms/c_1294071/roactemra-aji-synthese-09052012
http://www.has-sante.fr/portail/jcms/c_1250744/roactemra-09052012-avis-ct-11877
2012
false
France
French
evaluation of the transparency committee
tocilizumab
receptors, interleukin-6
tocilizumab
tocilizumab
arthritis, juvenile
child
treatment outcome
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized
infusions, intravenous
drug therapy, combination
continuity of patient care
clinical trials as topic
drug monitoring
risk management
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69582503
2012
France
summary of product characteristics
package leaflet
tocilizumab
---
https://www.ema.europa.eu/medicines/human/EPAR/RoActemra
2012
false
United Kingdom
French
English
injections, subcutaneous
syndication feed
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized
drug therapy, combination
receptors, interleukin-6
infusions, intravenous
pharmaceutical solutions
drug approval
treatment outcome
drug evaluation
arthritis, rheumatoid
drug interactions
pregnancy
breast feeding
Interleukin-6
drug evaluation, preclinical
adult
tocilizumab
tocilizumab
tocilizumab
arthritis, juvenile
child
adolescent
drug evaluation
summary of product characteristics
package leaflet
---
http://www.cochrane.org/fr/CD008331
2010
United Kingdom
France
French
meta-analysis
arthritis, rheumatoid
treatment outcome
antibodies, monoclonal, humanized
tocilizumab
french abstract
---
Summary Basis of Decision (SBD) ACTEMRA
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailOne.php?lang=fr&linkID=SBD00002
2010
false
Canada
French
English
antibodies, monoclonal, humanized
tocilizumab
antibodies, monoclonal
canada
receptors, interleukin-6
arthritis, rheumatoid
adult
tocilizumab
treatment outcome
drug approval
antibodies, monoclonal
drug evaluation
---
http://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2010/14066a-fra.php
http://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2010/14586a-fra.php
2010
Canada
English
French
tocilizumab
anaphylaxis
Interleukin-6
arthritis, rheumatoid
infusions, intravenous
tocilizumab
antibodies, monoclonal, humanized
pharmacovigilance note
patient education handout
drug hypersensitivity
antibodies, monoclonal
---
http://www.has-sante.fr/portail/jcms/c_893357/roactemra-tocilizumab-anticorps-monoclonal-anti-il6
2009
false
false
Haute Autorité de santé
France
French
guidelines for drug use
antibodies, monoclonal, humanized
arthritis, rheumatoid
pharmaceutical solutions
infusions, parenteral
tocilizumab
antibodies, monoclonal
tocilizumab
receptors, interleukin-6
treatment outcome
drug therapy, combination
adult
evaluation of the transparency committee
---
