Interleukin-6 - CISMeF

Preferred Label : Interleukin-6;

MeSH definition : A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.;

MeSH synonym : differentiation factor-2, b-cell; growth factor, hybridoma; il6; hybridoma growth factor; myeloid differentiation-inducing protein; plasmacytoma growth factor; growth factor, plasmacytoma; hepatocyte stimulating factor; b cell differentiation factor; b-cell differentiation factor-2; b cell differentiation factor 2; b-cell stimulatory factor 2; b-cell stimulatory factor-2; bsf-2; differentiation factor, b-cell; differentiation factor, b cell; differentiation factor 2, b cell; hepatocyte-stimulating factor; ifn-beta 2; il-6; mgi-2; differentiation-inducing protein, myeloid; myeloid differentiation inducing protein; b cell stimulatory factor-2; b cell stimulatory factor 2; b-cell differentiation factor; interleukin 6; Interferon beta-2; Interferon beta 2; beta-2, Interferon;

MeSH annotation : DF: IL 6 or IL6;

Wikipedia link : https://en.wikipedia.org/wiki/Interleukin 6;

Is substance : O;

Details

Origin ID

D015850;

UMLS CUI

C0021760;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Human Interleukin-6, Nonglycosylated [NCIt concept]
- IL6 Gene [NCIt concept]
- IL6 wt Allele [NCIt concept]
- Interleukin 6 [OMIM gene]
- Interleukin 6 Measurement [NCIt concept]
- interleukin 6 [ORDO Gene]
- interleukin 6 [HGNC gene]
- interleukin 6 [COVID-19 Thesaurus concept]
- interleukin-6 [Blood Transfusion thesaurus concept]
- interleukin-6 receptor binding [GO term]
Currated CISMeF NLP mapping
- Interleukin 6 [LOINC component]
- Interleukin-6 [FMA entity]
- Interleukin-6 [NCIt concept]
- Interleukin-6 [MedDRA LLT]
- Interleukin-6 (substance) [SNOMED CT concept]
- interleukin-6 [SNOMED Notion]
Indexing information
- 12-hydroxyscabrolide A [MeSH Supplementary Concept]
- 2-amino-4-(4-chlorophenyl)-5-methylthiazole [MeSH Supplementary Concept]
- CGP 47969A [MeSH Supplementary Concept]
- TJU 103 [MeSH Supplementary Concept]
- duanbanhuain A [MeSH Supplementary Concept]
- duanbanhuain B [MeSH Supplementary Concept]
- quercetin 3-O-(2''-galloyl)glucopyranoside [MeSH Supplementary Concept]
- scabrolide C [MeSH Supplementary Concept]
Record concept(s)
- Interleukin-6 [MeSH concept]
Related MeSH Supplementary Concept(s)
- 22-interleukin-6 cysteine(3,4) [MeSH Supplementary Concept]
- DAB(389)-interleukin 6 [MeSH Supplementary Concept]
- IL-6-PE40 protein, chimeric [MeSH Supplementary Concept]
- IL6 protein, human [MeSH Supplementary Concept]
- Il6 protein, rat [MeSH Supplementary Concept]
- SANT-7 [MeSH Supplementary Concept]
- interleukin 6-interleukin 6 receptor fusion protein, recombinant [MeSH Supplementary Concept]
- interleukin-6, 2-nitrophenylsulfenyl-Trp(36,160)- [MeSH Supplementary Concept]
- interleukin-6, RRV-HHV-8 [MeSH Supplementary Concept]
- interleukin-6, mouse [MeSH Supplementary Concept]
- interleukin-6-PE66(4Glu) chimeric protein, recombinant [MeSH Supplementary Concept]
- neuropoietin, mouse [MeSH Supplementary Concept]
- recombinant fusion protein IL-6 - IL-2 [MeSH Supplementary Concept]
See also
- hybridomas [MeSH Descriptor]
- plasmacytoma [MeSH Descriptor]
See also (suggested by CISMeF)
- receptors, interleukin-6 [MeSH Descriptor]
- sirukumab [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Interleukin 6 [LOINC component]
- Interleukin-6 [FMA entity]
- Interleukin-6 (substance) [SNOMED CT concept]
- interleukin-6 [SNOMED Notion]
Validated automatic mappings to BTNT
- Recombinant Interleukin-6 [NCIt concept]

Keyword's position in hierarchy(ies) :

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