Preferred Label : midostaurin;

MeSH note : structure given in first source; staurosporine analog;

CISMeF synonym : CGP 41251;

MeSH synonym : 4'-N-benzoyl staurosporine; benzoylstaurosporine; 4'-N-benzoylstaurosporine; N-((9S,10R,11R,13R)-10-methoxy-9-methyl-1-oxo-2,3,10,11,12,13-hexahydro-9,13-epoxy-1H,9H-diindolo(1,2,3-GH:3',2',1'-lm)pyrrolo(3,4-j)(1,7)benzodiazonin-11-yl)-n-methylbenzamide; benzamide, N-(2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-1-oxo-8,12-epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-10-yl)-N-methyl-, (8alpha,9beta,10beta,12alpha)-;

MeSH hyponym : CGP 41 251; CGP-41251; PKC-412; PKC 412;

MeSH CAS label : benzamide, N-(2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-1-oxo-8,12-epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-10-yl)-N-methyl-, (8alpha,9beta,10beta,12alpha)-;

MeSH Related Number : 120685-11-2;

Registry Number MeSH : 120685-11-2;

Is substance : O;

UNII : ID912S5VON;

Details


Main resources

You can consult :


https://www.has-sante.fr/jcms/p_3240418/fr/rydapt
2021
false
false
false
France
treatment outcome
insurance, health, reimbursement
midostaurin
antineoplastic agents
protein kinase inhibitors
administration, oral
midostaurin
adult
aggressive systemic mastocytosis
Systemic mastocytosis with associated hematologic neoplasm
evaluation of the transparency committee
mastocytosis, systemic
staurosporine
staurosporine

---
https://www.has-sante.fr/portail/jcms/c_2862069/fr/rydapt-lam
2018
false
false
false
false
France
French
evaluation of the transparency committee
midostaurin
midostaurin
treatment outcome
midostaurin
administration, oral
antineoplastic agents
antineoplastic agents
adult
antineoplastic combined chemotherapy protocols
leukemia, myeloid, acute
FLT3 Gene Mutation
leukemia, myeloid, acute
staurosporine
staurosporine
staurosporine

---
https://www.has-sante.fr/portail/jcms/c_2861089/fr/rydapt-mastocytose
https://www.has-sante.fr/portail/jcms/c_2861089/fr/rydapt-midostaurine-inhibiteur-de-tyrosine-kinase-mastocytose
2018
false
false
false
false
France
French
evaluation of the transparency committee
administration, oral
aggressive systemic mastocytosis
midostaurin
midostaurin
treatment outcome
midostaurin
Systemic mastocytosis with associated hematologic neoplasm
leukemia, mast-cell
guidelines for drug use
mastocytosis, systemic
staurosporine
staurosporine
staurosporine

---
https://www.has-sante.fr/portail/jcms/c_2879339/fr/rydapt
2018
false
true
false
France
leukemia, myeloid, acute
midostaurin
antineoplastic agents
midostaurin
evaluation of the transparency committee
staurosporine
staurosporine

---
https://ansm.sante.fr/tableau-atu-rtu/midostaurine-25-mg-capsule-molle
2016
false
false
false
France
French
guidelines for drug use
summary of product characteristics
package leaflet
midostaurin
midostaurin
midostaurin
capsules
staurosporine
staurosporine
staurosporine

---
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19/05/2024


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