Preferred Label : levoleucovorin;
MeSH definition : A folate analog consisting of the pharmacologically active isomer of LEUCOVORIN.;
MeSH synonym : leucovorin, (S)-Isomer; 6-S-leucovorin; 6 S leucovorin; S-leucovorin; S leucovorin; levo-leucovorin; levo leucovorin; (6S)-leucovorin; 6S-leucovorin; 6S leucovorin;
CISMeF synonym : L-FOLINIC ACID;
MeSH hyponym : fusilev; leucovorin, monopotassium salt, (S)-Isomer; leucovorin, calcium (1:1) salt, (S)-Isomer; leucovorin, monosodium salt, (S)-Isomer;
MeSH Related Number : leucovorin, monosodium salt, (S)-Isomer; leucovorin, monopotassium salt, (S)-Isomer; leucovorin, calcium (1:1) salt, (S)-Isomer; 68538-85-2 (Levoleucovorin); 122291-98-9; 122291-99-0; 80433-71-2;
Registry Number MeSH : 68538-85-2;
Related CAS MeSH : 122291-98-9 (Leucovorin, monosodium salt, (S)-Isomer); 122291-99-0 (Leucovorin, monopotassium salt, (S)-Isomer); 80433-71-2 (Leucovorin, calcium (1:1) salt, (S)-Isomer);
Is substance : O;
UNII : 990S25980Y;
InChIKey : VVIAGPKUTFNRDU-STQMWFEESA-N;
Origin ID : D058766;
UMLS CUI : C2721771;
ATC code(s)
Allowable qualifiers
Currated CISMeF NLP mapping
Pharmacological action(s)
Record concept(s)
Related MeSH Supplementary Concept(s)
Semantic type(s)
UMLS correspondences (same concept)
A folate analog consisting of the pharmacologically active isomer of LEUCOVORIN.
https://ansm.sante.fr/disponibilites-des-produits-de-sante/medicaments/elvorine-25-mg-2-5-ml-50-mg-5-ml-100-mg-10-ml-et-175-mg-17-5-ml-solution-injectable-levofolinate-de-calcium
2025
false
false
false
France
French
drug information
leucovorin, calcium (1:1) salt, (S)-Isomer
levoleucovorin
---
https://www.has-sante.fr/jcms/p_3637616/fr/levofolinate-de-calcium-zentiva-acide-levofolinique-oncologie-/-carence-en-folates
2025
false
false
false
France
antidotes
treatment outcome
insurance, health, reimbursement
antineoplastic combined chemotherapy protocols
Methotrexate Toxicity
Leukovorin rescue (procedure)
folic acid antagonists
methotrexate
Chemosensitization
Methotrexate overdose (disorder)
infusions, intravenous
injections, intravenous
injections, intramuscular
calcium levofolinate
evaluation of the transparency committee
folic acid deficiency
leucovorin, calcium (1:1) salt, (S)-Isomer
levoleucovorin
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69444559
2012
France
summary of product characteristics
package leaflet
leucovorin, calcium (1:1) salt, (S)-Isomer
injections
levoleucovorin
powders
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60140836
2012
France
summary of product characteristics
package leaflet
powders
levoleucovorin
injections
leucovorin, calcium (1:1) salt, (S)-Isomer
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68355004
2012
France
summary of product characteristics
package leaflet
leucovorin, calcium (1:1) salt, (S)-Isomer
powders
injections
levoleucovorin
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64690336
2012
France
summary of product characteristics
package leaflet
levoleucovorin
injections
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67126522
2012
France
summary of product characteristics
package leaflet
leucovorin, calcium (1:1) salt, (S)-Isomer
injections
powders
levoleucovorin
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64127601
2012
France
summary of product characteristics
package leaflet
leucovorin, calcium (1:1) salt, (S)-Isomer
levoleucovorin
injections
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68634071
2012
France
summary of product characteristics
package leaflet
levoleucovorin
leucovorin, calcium (1:1) salt, (S)-Isomer
injections
---
http://www.has-sante.fr/upload/docs/application/pdf/2011-11/elvorine_19-10-2011_avis_ct-11397.pdf
http://www.has-sante.fr/jcms/c_1118587/elvorine
2011
false
France
French
evaluation of the transparency committee
leucovorin, calcium (1:1) salt, (S)-Isomer
levoleucovorin
antidotes
injections
folic acid antagonists
Drug-Related side effects and adverse reactions
calcium levofolinate
insurance, health, reimbursement
antineoplastic combined chemotherapy protocols
adult
child
Leukovorin rescue (procedure)
colorectal neoplasms
fluorouracil
treatment outcome
---
http://www.has-sante.fr/display.jsp?id=c_621752
2008
false
France
French
antineoplastic combined chemotherapy protocols
fluorouracil
drug synergism
antidotes
levoleucovorin
leucovorin, calcium (1:1) salt, (S)-Isomer
Leukovorin rescue (procedure)
calcium levofolinate
guidelines for drug use
---
http://www.has-sante.fr/display.jsp?id=c_399980
2004
France
evaluation of the transparency committee
leucovorin, calcium (1:1) salt, (S)-Isomer
injections
powders
levoleucovorin
---