caspase 9 - CISMeF

Preferred Label : caspase 9;

MeSH definition : A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.;

MeSH synonym : ice like apoptotic protease 6; ICE-Like Apoptotic Protease 6; apoptotic protease activating factor 3; ice-lap6 protein; ice lap6 protein; Caspase-9;

MeSH hyponym : Procaspase-9; Procaspase 9; Pro-Caspase-9; Pro Caspase 9;

Registry Number MeSH : EC 3.4.22.-;

MeSH annotation : Do not confuse with CAS9 ENZYME see CRISPR-ASSOCIATED PROTEIN 9;

Is substance : O;

Details

Origin ID

D053453;

UMLS CUI

C0910167;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- CASP9 wt Allele [NCIt concept]
- Caspase 9, apoptosis-related cysteine protease [OMIM gene]
- Caspase-2 [NCIt concept]
- Caspase-3 [NCIt concept]
- Caspase-5 [NCIt concept]
- Caspase-6 [NCIt concept]
- Caspase-7 [NCIt concept]
- Cathepsin Z [NCIt concept]
- Cysteine Proteinase [NCIt concept]
- caspase 9 [HGNC gene]
Record concept(s)
- Procaspase-9 [MeSH concept]
- caspase 9 [MeSH concept]
Related MeSH Supplementary Concept(s)
- CASP9 protein, human [MeSH Supplementary Concept]
- Casp9 protein, mouse [MeSH Supplementary Concept]
- Casp9 protein, rat [MeSH Supplementary Concept]
- ICE-2 protein, Bombyx mori [MeSH Supplementary Concept]
Related MeSH term(s)
- caspase inhibitors [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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