caspase 3 - CISMeF

Preferred Label : caspase 3;

MeSH definition : A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.;

MeSH synonym : casp3; apopain; Caspase-3;

MeSH hyponym : Procaspase-3; Procaspase 3; Pro-Caspase-3; Pro Caspase 3;

MeSH Related Number : Procaspase-3;

Registry Number MeSH : EC 3.4.22.-;

Related CAS MeSH : EC 3.4.22.- (Procaspase-3);

Wikipedia link : https://en.wikipedia.org/wiki/Caspase 3;

Is substance : O;

Details

Origin ID

D053148;

UMLS CUI

C0291573;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- CASP3 Gene [NCIt concept]
- Caspase 3, apoptosis-related cysteine protease [OMIM gene]
- Caspase-2 [NCIt concept]
- Caspase-5 [NCIt concept]
- Caspase-6 [NCIt concept]
- Caspase-7 [NCIt concept]
- Caspase-9 [NCIt concept]
- Cathepsin Z [NCIt concept]
- Cysteine Proteinase [NCIt concept]
- caspase 3 [HGNC gene]
Indexing information
- 1-(4-(2-fluoroethoxy)benzyl)-5-(1-(2-methoxymethylpyrrolidinyl)sulfonyl)isatin [MeSH Supplementary Concept]
- 4-(ethoxycarbonylmethoxy)-1-hydroxy-2-naphthoic acid [MeSH Supplementary Concept]
- DEVDase [MeSH Supplementary Concept]
- benzyloxycarbonyl-tert-leucyl-aspartic acid [MeSH Supplementary Concept]
Record concept(s)
- Procaspase-3 [MeSH concept]
- caspase 3 [MeSH concept]
Related MeSH Supplementary Concept(s)
- CASP3 protein, human [MeSH Supplementary Concept]
- Casp3 protein, mouse [MeSH Supplementary Concept]
- Casp3 protein, rat [MeSH Supplementary Concept]
Related MeSH term(s)
- caspase inhibitors [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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