saposins - CISMeF

Preferred Label : saposins;

MeSH definition : A group of four homologous sphingolipid activator proteins that are formed from proteolytic cleavage of a common protein precursor molecule referred to as prosaposin.;

MeSH synonym : testibumin; Saposin;

MeSH hyponym : saposin B; saposin D; saposin C; saposin A; Sphingolipid Activator Protein 1; Sphingolipid Activator Protein-1; SAP-1 Sphingolipid Activator; SAP 1 Sphingolipid Activator; Sphingolipid Activator, SAP-1; SAP-D Protein; SAP D Protein; SAP-A Protein; SAP A Protein; beta-Glucosidase Stimulating Protein; beta Glucosidase Stimulating Protein; Co-beta-Glucosidase; Co beta Glucosidase; Sphingolipid Activator Protein 2; Gaucher Activator Protein; Glucosylceramidase Activator; SAP-C Protein; SAP C Protein; beta-Glucosidase Activator Protein; beta Glucosidase Activator Protein; Coglucosidase;

Is substance : O;

Details

Origin ID

D049231;

UMLS CUI

C0076175;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Beta glucosidase [OBSOLETE LOINC component]
- Prosaposin [NCIt concept]
- Prosaposin [OMIM gene]
- Saposin-A [NCIt concept]
- Saposin-B [NCIt concept]
- Saposin-C [NCIt concept]
- Saposin-D [NCIt concept]
- glucosylceramidase activity [GO term]
- sphingolipid activator protein activity [GO term]
Record concept(s)
- saposin A [MeSH concept]
- saposin B [MeSH concept]
- saposin C [MeSH concept]
- saposin D [MeSH concept]
- saposins [MeSH concept]
Related MeSH Supplementary Concept(s)
- PSAP protein, human [MeSH Supplementary Concept]
- VSA-2 [MeSH Supplementary Concept]
- combined saposin deficiency [MeSH Supplementary Concept]
- gaucher disease, atypical, due to saposin C deficiency [MeSH Supplementary Concept]
- krabbe disease, atypical, due to saposin A deficiency [MeSH Supplementary Concept]
- metachromatic leukodystrophy due to saposin B deficiency [MeSH Supplementary Concept]
- psap protein, mouse [MeSH Supplementary Concept]
- psap protein, rat [MeSH Supplementary Concept]
- saposin A, mouse [MeSH Supplementary Concept]
- saposin B, mouse [MeSH Supplementary Concept]
- silenoviscoside F [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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