Saposin-A - CISMeF

Preferred Label : Saposin-A;

NCIt synonyms : Saposin A; SAPA; Protein A;

NCIt definition : Saposin-A (83 aa, 9 kDa) is encoded by the human PSAP gene. This protein is involved in promoting the hydrolysis of glucosylceramide and galactosylceramide by beta-glucosylceramidase and beta-galactosylceramidase, respectively.;

NCIt note : Saposin-A is comprised of amino acids 60 - 142 of prosaposin.;

NCI Metathesaurus CUI : CL1778818;

Details

Origin ID

C186553;

UMLS CUI

C5575473;

Automatic exact mappings (from CISMeF team)
- Prosaposin [OMIM gene]
- Protein [LOINC component]
- Protein [MedDRA LLT]
- Protein [FMA entity]
- Protein (substance) [SNOMED CT concept]
- Proteins [PASCAL theme]
- Proteins [DeCS]
- Proteins [PASCAL theme]
- Proteins [UNESCO concept]
- Proteins [HPMULTI term]
- Wasp actin nucleation promoting factor [OMIM gene]
- ataxia telangiectasia mutated proteins [MeSH Descriptor]
- dietary proteins [MedlinePlus Topic]
- prosaposin [ORDO Gene]
- prosaposin [HGNC gene]
- protein [Radlex concept]
- protein [OBI concept]
- protein [Artificial nutrition thesaurus concept]
- protein [Blood Transfusion thesaurus concept]
- protein marker [COVID-19 Thesaurus concept]
- proteins [MeSH Descriptor]
- proteins [MeSH concept]
- proteins [IUPAC Term]
- saposin A [MeSH concept]
- saposins [MeSH Descriptor]
- saposins [MeSH concept]
- sphingolipid activator protein activity [GO term]
- staphylococcal protein a [MeSH Descriptor]
OMIM relation
- Prosaposin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- PSAP Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Lysosome [NCIt concept]
gene_product_is_element_in_pathway
- Sphingolipid Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Lipid Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients