Preferred Label : ataxia telangiectasia mutated proteins;
MeSH definition : A group of PROTEIN-SERINE-THREONINE KINASES which activate critical signaling cascades
in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet
A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide
range of signaling mechanisms in cell cycle control.; A group of PROTEIN SERINE-THREONINE KINASES which activate critical signaling cascades
in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet
A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide
range of signaling mechanisms in cell cycle control.;
MeSH synonym : AT mutated protein; mutated protein, AT; protein, AT mutated; ATM protein; A-T protein; A T protein; protein, A-T;
Registry Number MeSH : EC 2.7.11.1;
Is substance : O;
UNII : EC 2.7.11.1;
Origin ID : D064007;
UMLS CUI : C0298973;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- protein [Blood Transfusion thesaurus concept]
- protein [Artificial nutrition thesaurus concept]
- Indexing information
- KU59403 [MeSH Supplementary Concept]
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
A group of PROTEIN-SERINE-THREONINE KINASES which activate critical signaling cascades
in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet
A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide
range of signaling mechanisms in cell cycle control.
A group of PROTEIN SERINE-THREONINE KINASES which activate critical signaling cascades
in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet
A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide
range of signaling mechanisms in cell cycle control.
