MAP kinase kinase kinases

Preferred Label : MAP kinase kinase kinases;

MeSH definition : Mitogen-activated protein kinase kinase kinases (MAPKKKs) are serine-threonine protein kinases that initiate protein kinase signaling cascades. They phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES; (MAPKKs) which in turn phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs).;

MeSH synonym : mitogen-activated protein kinase kinase kinases; kinases, map kinase kinase; map kinase kinase kinase; mapkkks; mitogen activated protein kinase kinase kinases; map3 kinases; kinases, map3; MAPKKK; Mitogen-Activated Protein Kinase Kinase Kinase; Mitogen Activated Protein Kinase Kinase Kinase; MAP3 Kinase; Kinase, MAP3;

CISMeF synonym : EC 2.7.1.37;

MeSH hyponym : MAPK-ERK kinase kinases; Kinase Kinases, MAPK-ERK; Kinases, MAPK-ERK Kinase; MAPK ERK Kinase Kinases; MEK Kinases; Kinases, MEK; MEKKs; MEK Kinase; Kinase, MEK; MAPK-ERK Kinase Kinase; Kinase Kinase, MAPK-ERK; Kinase, MAPK-ERK Kinase; MAPK ERK Kinase Kinase; MEKK;

MeSH Related Number : MAPK-ERK kinase kinases; EC 2.7.11.25;

Registry Number MeSH : EC 2.7.11.25;

Related CAS MeSH : EC 2.7.11.25 (MAPK-ERK kinase kinases);

Wikipedia link : https://en.wikipedia.org/wiki/Map kinase kinase kinases;

Is substance : O;

UNII : EC 2.7.11.25;

Details

Origin ID

D020930;

UMLS CUI

C0211705;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- MAP Kinase Gene [NCIt concept]
- MAP kinase kinase kinase activity [GO term]
- MAP3K1 wt Allele [NCIt concept]
- Mitogen-Activated Protein Kinase [NCIt concept]
- Mitogen-Activated Protein Kinase Kinase Kinase 1 [NCIt concept]
- Mitogen-activated protein kinase kinase kinase 1 [OMIM gene]
- mitogen-activated protein kinase kinase kinase 1 [ORDO Gene]
Record concept(s)
- MAP kinase kinase kinases [MeSH concept]
- MAPK-ERK kinase kinases [MeSH concept]
Related MeSH Supplementary Concept(s)
- ANP1 kinase [MeSH Supplementary Concept]
- ANP2 protein, Arabidopsis [MeSH Supplementary Concept]
- ANP3 protein, Arabidopsis [MeSH Supplementary Concept]
- ASK1 protein, Drosophila [MeSH Supplementary Concept]
- At1g73660 protein, arabidopsis [MeSH Supplementary Concept]
- BCK1 protein, pneumocystis carinii [MeSH Supplementary Concept]
- BYR2 protein, S pombe [MeSH Supplementary Concept]
- DLK-1 protein, C elegans [MeSH Supplementary Concept]
- Lzk protein, mouse [MeSH Supplementary Concept]
- MAP kinase kinase kinase 6 [MeSH Supplementary Concept]
- MAP kinase kinase kinase 7 [MeSH Supplementary Concept]
- MAP kinase kinase kinase ubc4 [MeSH Supplementary Concept]
- MAP3K10 protein, human [MeSH Supplementary Concept]
- MAP3K13 protein, human [MeSH Supplementary Concept]
- MAP3K15 protein, human [MeSH Supplementary Concept]
- MAP3K19 protein, human [MeSH Supplementary Concept]
- MAP3K2 protein, human [MeSH Supplementary Concept]
- MAP3K20 protein, human [MeSH Supplementary Concept]
- MAP3K21 protein, human [MeSH Supplementary Concept]
- MAP3K8 protein, human [MeSH Supplementary Concept]
- MAP3K9 protein, human [MeSH Supplementary Concept]
- MAP3Kepsilon2 protein, arabidopsis [MeSH Supplementary Concept]
- MAPKKK18 protein, Arabidopsis [MeSH Supplementary Concept]
- MEKK1 protein, Arabidopsis [MeSH Supplementary Concept]
- MLK-like mitogen-activated protein triple kinase [MeSH Supplementary Concept]
- Map3k10 protein, mouse [MeSH Supplementary Concept]
- Map3k15 protein, mouse [MeSH Supplementary Concept]
- Map3k8 protein, mouse [MeSH Supplementary Concept]
- Map3k8 protein, rat [MeSH Supplementary Concept]
- Map3k9 protein, mouse [MeSH Supplementary Concept]
- Map3k9 protein, rat [MeSH Supplementary Concept]
- Mkh1 protein, S pombe [MeSH Supplementary Concept]
- NPK1 protein, nicotiana tabacum [MeSH Supplementary Concept]
- REKS protein, xenopus [MeSH Supplementary Concept]
- Raf1 protein, rat [MeSH Supplementary Concept]
- Raf10 protein, Arabidopsis [MeSH Supplementary Concept]
- Raf11 protein, Arabidopsis [MeSH Supplementary Concept]
- Raf43 protein, Arabidopsis [MeSH Supplementary Concept]
- SSK2 protein, S cerevisiae [MeSH Supplementary Concept]
- SSK22 protein, S cerevisiae [MeSH Supplementary Concept]
- STE20 protein, S cerevisiae [MeSH Supplementary Concept]
- Ste11 protein, S cerevisiae [MeSH Supplementary Concept]
- TAK1 protein, Drosophila [MeSH Supplementary Concept]
- TAO1 protein kinase [MeSH Supplementary Concept]
- TNNI3K protein, human [MeSH Supplementary Concept]
- Taok2 protein, rat [MeSH Supplementary Concept]
- YODA protein, arabidopsis [MeSH Supplementary Concept]
- ZAK protein, mouse [MeSH Supplementary Concept]
- insulin-stimulated MEK kinase [MeSH Supplementary Concept]
- map3k10 protein, Xenopus [MeSH Supplementary Concept]
- mitogen-activated protein kinase kinase kinase 11 [MeSH Supplementary Concept]
- mitogen-activated protein kinase kinase kinase 12 [MeSH Supplementary Concept]
- ras-dependent mitogen-activated protein kinase kinase kinase [MeSH Supplementary Concept]
- slpr protein, drosophila [MeSH Supplementary Concept]
- wis4 protein, S pombe [MeSH Supplementary Concept]
- wnd protein, Drosophila [MeSH Supplementary Concept]
See also
- map kinase signaling system [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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