Preferred Label : Map3k8 protein, mouse;
MeSH note : Tpl-2 is thehomolog of human cot; a MAP3K kinase involved in the progression of rodent
T-cell lymphomas & in T-cell activation; it up-regulates COX-2 gene expression in
Jurkat T cells; It binds and induces NF-B-dependent transcription; RefSeq NM_007746;
MeSH synonym : Tpl-2 protein, mouse; tumor progression locus 2 protein, mouse; cancer osaka thyroid kinase, mouse; mitogen activated protein kinase kinase kinase 8, mouse; sluggish protein, mouse; c-COT protein, mouse; Tpl2 protein, mouse;
Registry Number MeSH : EC 2.7.10.-; EC 2.7.11.25;
Is substance : O;
UNII : EC 2.7.11.25;
Origin ID : C489843;
UMLS CUI : C1435851;
MeSH term(s) associated for indexing
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