MAP3K1 wt Allele

Preferred Label : MAP3K1 wt Allele;

NCIt synonyms : MEKK; MAPKKK1; Mitogen-Activated Protein Kinase Kinase Kinase 1 wt Allele; MEKK1; SRXY6;

NCIt definition : Human MAP3K1 wild-type allele is located in the vicinity of 5q11.2 and is approximately 82 kb in length. This allele, which encodes mitogen-activated protein kinase kinase kinase 1 protein, plays a role in the protein kinase signal transduction cascade.;

NCIt note : A SNP has been identified in the MAP3K1 gene (rs889312), which is associated with increases in breast cancer incidence. (Nature 2007; 447:1087-1093);

GenBank Accession Number : U29671;

PubMed : 17529967;

Details

Origin ID

C50392;

UMLS CUI

C1708800;

OMIM relation
- Mitogen-activated protein kinase kinase kinase 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 5q11.2 [NCIt concept]
gene_is_element_in_pathway
- 4-1BB-Dependent Immune Response Pathway [NCIt concept]
- Angiotensin II Signaling Pathway [NCIt concept]
- BCR Signaling Pathway [NCIt concept]
- CD40L Signaling Pathway [NCIt concept]
- Ceramide Signaling Pathway BioCarta [NCIt concept]
- EGF Signaling Pathway [NCIt concept]
- Fas Signaling Pathway BioCarta [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway BioCarta [NCIt concept]
- Formyl Peptide Receptor 1 Signaling Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- HIV-I Nef in Apoptosis Pathway [NCIt concept]
- Human Cytomegalovirus Infection Pathway [NCIt concept]
- IL1R Signaling Pathway [NCIt concept]
- Inhibition of Cellular Proliferation by Gleevec Pathway [NCIt concept]
- Keratinocyte Differentiation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- Map Kinase Inactivation of SMRT Corepressor Pathway [NCIt concept]
- NFKB Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- PDGF Signaling Pathway [NCIt concept]
- Pyk2 and Map Kinase Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- Rac1 Cell Motility Signaling Pathway [NCIt concept]
- SRF Activation Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway BioCarta [NCIt concept]
- T-Cell Antiapoptosis Pathway [NCIt concept]
- TNFR1 Signaling Pathway [NCIt concept]
- TNFR2 Signaling Pathway [NCIt concept]
- Toll-Like Receptor Pathway [NCIt concept]
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
- p38 MAPK Signaling Pathway BioCarta [NCIt concept]
gene_plays_role_in_process
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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