Preferred Label : Map3k8 protein, rat;
MeSH note : Tpl-2 is the rat homolog of human cot; a MAP3K kinase involved in the progression
of rodent T-cell lymphomas & in T-cell activation; it up-regulates COX-2 gene expression
in Jurkat T cells; It binds and induces NF-B-dependent transcription; RefSeq NM_053847;
MeSH synonym : Tpl2 protein, rat; mitogen-activated protein kinase kinase kinase 8, rat; tumor progression locus 2 protein, rat; cancer osaka thyroid kinase, rat;
Registry Number MeSH : EC 2.7.10.-; EC 2.7.11.25;
Is substance : O;
UNII : EC 2.7.11.25;
Origin ID : C080356;
UMLS CUI : C1505123;
MeSH term(s) associated for indexing
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