Preferred Label : loratadine;
MeSH definition : A second-generation histamine H1 receptor antagonist used in the treatment of allergic
rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS)
it lacks central nervous system depressing effects such as drowsiness.;
MeSH synonym : 4-(8-Chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylic
Acid Ethyl Ester;
CISMeF synonym : wyeth brand of loratadine; loratadine wyeth brand;
MeSH hyponym : alavert; claritin; Sch-29851; clarium; Sch 29851; Sch29851;
MeSH CAS label : 1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-,
ethyl ester;
MeSH Related Number : 79794-75-5 (Loratadine);
Registry Number MeSH : 79794-75-5;
Wikipedia link : https://en.wikipedia.org/wiki/Loratadine;
Is substance : O;
UNII : 7AJO3BO7QN;
InChIKey : JCCNYMKQOSZNPW-UHFFFAOYSA-N;
Origin ID : D017336;
UMLS CUI : C0065180;
ATC code(s)
Allowable qualifiers
CISMeF manual mappings
Currated CISMeF NLP mapping
Pharmacological action(s)
Record concept(s)
Related MeSH Supplementary Concept(s)
- sch 434 [MeSH Supplementary Concept]
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
A second-generation histamine H1 receptor antagonist used in the treatment of allergic
rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS)
it lacks central nervous system depressing effects such as drowsiness.
https://www.sfdermato.org/media/pdf/recommandation/prise-en-charge-de-urticaire-chronique-spontanee-471b6ebe79d8a3e8103790b3250d1aa5.pdf
2019
false
false
false
France
chronic disease
Chronic spontaneous urticaria
desloratadine
urticaria
histamine h1 antagonists
case reports
Omalizumab
cyclosporine
overweight
angioedema
dexchlorpheniramine
drug therapy, combination
risk factors
cetirizine
levocetirizine
adult
child
pregnancy
practice guideline
urticaria
patient care management
loratadine
loratadine
chlorpheniramine
---
https://www.has-sante.fr/portail/jcms/c_2824488/fr/clarityne
2018
false
false
false
false
France
French
evaluation of the transparency committee
loratadine
administration, oral
treatment outcome
histamine H1 antagonists, non-sedating
claritin
loratadine
---
http://www.has-sante.fr/portail/jcms/c_2746927/fr/aerius
2017
false
false
false
France
French
evaluation of the transparency committee
insurance, health, reimbursement
desloratadine
desloratadine
loratadine
---
https://www.hc-sc.gc.ca/dhp-mps/medeff/bulletin/hpiw-ivps_2016-12-fra.php#lora
2016
false
false
false
Canada
French
English
drug evaluation
long qt syndrome
risk assessment
loratadine
loratadine
product surveillance, postmarketing
anti-allergic agents
---
http://www.has-sante.fr/portail/jcms/c_1776987/fr/desloratadine-mylan
2014
false
false
false
France
French
evaluation of the transparency committee
desloratadine
loratadine
---
http://www.meddispar.fr/Medicaments/DOLIALLERGIE-LORATADINE-10-B-7/(type)/letter/(value)/D/(cip)/3400949819058
2014
false
false
false
France
French
drug information
loratadine
loratadine
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66281402
2012
France
summary of product characteristics
package leaflet
loratadine
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61010258
2012
France
summary of product characteristics
package leaflet
loratadine
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67258709
2012
France
summary of product characteristics
package leaflet
loratadine
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65739672
2012
France
summary of product characteristics
package leaflet
loratadine
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62367569
2012
France
summary of product characteristics
package leaflet
loratadine
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62980675
2012
France
summary of product characteristics
package leaflet
loratadine
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67091719
2012
France
summary of product characteristics
package leaflet
loratadine
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69033038
2012
France
summary of product characteristics
package leaflet
sarraceniaceae
loratadine
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68728738
2012
France
summary of product characteristics
package leaflet
hypersensitivity
tablets
loratadine
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68017159
2012
France
summary of product characteristics
package leaflet
tablets
loratadine
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67918713
2012
France
summary of product characteristics
package leaflet
tablets
loratadine
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63511727
2012
France
summary of product characteristics
package leaflet
loratadine
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68468589
2012
France
summary of product characteristics
package leaflet
tablets
loratadine
---
http://www.meddispar.fr/Medicaments/HUMEX-ALLERGIE-LORATADINE-10-B-7/(type)/letter/(value)/H/(cip)/3400949894338
2012
France
drug information
hypersensitivity
loratadine
---
https://www.ema.europa.eu/medicines/human/EPAR/Aerinaze
2012
United Kingdom
English
French
syndication feed
Contraindications, Procedure
loratadine
loratadine
loratadine
loratadine
pseudoephedrine
pseudoephedrine
nasal decongestants
nasal decongestants
adult
drug combinations
treatment outcome
adolescent
tablets
Delayed-Action preparations
nasal obstruction
pseudoephedrine
pseudoephedrine
drug evaluation
administration, oral
loratadine
pseudoephedrine
histamine H1 antagonists, non-sedating
nasal decongestants
nasal decongestants
drug interactions
pregnancy
breast feeding
pseudoephedrine
nasal decongestants
histamine H1 antagonists, non-sedating
pseudoephedrine
nasal decongestants
histamine H1 antagonists, non-sedating
drug evaluation, preclinical
pseudoephedrine
nasal decongestants
histamine H1 antagonists, non-sedating
drug labeling
histamine H1 antagonists, non-sedating
drug approval
loratadine
loratadine
loratadine
histamine H1 antagonists, non-sedating
rhinitis, allergic, seasonal
histamine H1 antagonists, non-sedating
desloratadine
pseudoephedrine, combinations
package leaflet
summary of product characteristics
drug evaluation
Contraindications, Drug
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68891863
2012
France
summary of product characteristics
package leaflet
loratadine
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64253639
2012
France
summary of product characteristics
package leaflet
tablets
loratadine
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61007493
2012
France
summary of product characteristics
package leaflet
loratadine
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63669741
2012
France
summary of product characteristics
package leaflet
loratadine
tablets
---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2012-03/aerius_15_02_2012_avis_ct-11839.pdf
http://www.has-sante.fr/portail/jcms/c_1219565/aerius
2012
France
French
evaluation of the transparency committee
desloratadine
administration, oral
desloratadine
loratadine
insurance, health, reimbursement
rhinitis, allergic, seasonal
rhinitis, allergic, perennial
urticaria
histamine H1 antagonists, non-sedating
treatment outcome
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67432693
2012
France
summary of product characteristics
package leaflet
tablets
loratadine
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67634570
2012
France
summary of product characteristics
package leaflet
loratadine
tablets
---
https://www.ema.europa.eu/medicines/human/EPAR/desloratadine-ratiopharm
2012
false
United Kingdom
French
English
syndication feed
desloratadine
desloratadine
loratadine
desloratadine
administration, oral
drugs, generic
drug approval
treatment outcome
histamine H1 antagonists, non-sedating
histamine H1 antagonists, non-sedating
pregnancy
breast feeding
urticaria
rhinitis, allergic, seasonal
rhinitis, allergic, perennial
adolescent
adult
drug evaluation
summary of product characteristics
package leaflet
---
https://www.ema.europa.eu/medicines/human/EPAR/desloratadine-actavis
2012
false
United Kingdom
French
English
syndication feed
desloratadine
desloratadine
administration, oral
drugs, generic
drug approval
treatment outcome
desloratadine
loratadine
rhinitis, allergic, seasonal
rhinitis, allergic, perennial
urticaria
adult
adolescent
pregnancy
breast feeding
histamine H1 antagonists, non-sedating
histamine H1 antagonists, non-sedating
drug evaluation
summary of product characteristics
package leaflet
---
https://www.ema.europa.eu/medicines/human/EPAR/Dasselta
2012
United Kingdom
English
French
drug evaluation
summary of product characteristics
package leaflet
syndication feed
desloratadine
desloratadine
drug approval
treatment outcome
administration, oral
drugs, generic
histamine H1 antagonists, non-sedating
histamine H1 antagonists, non-sedating
adolescent
adult
rhinitis, allergic, seasonal
rhinitis, allergic, perennial
urticaria
desloratadine
pregnancy
breast feeding
drug interactions
drug evaluation, preclinical
loratadine
---
https://www.ema.europa.eu/medicines/human/EPAR/Desloratadine-Teva
2012
United Kingdom
French
English
drug evaluation
package leaflet
summary of product characteristics
syndication feed
histamine h1 antagonists
histamine h1 antagonists
loratadine
drugs, generic
administration, oral
rhinitis, allergic, perennial
rhinitis, allergic, seasonal
urticaria
adult
adolescent
pregnancy
breast feeding
desloratadine
desloratadine
drug approval
treatment outcome
desloratadine
---
http://www.has-sante.fr/portail/display.jsp?id=c_455280
http://www.has-sante.fr/portail/jcms/c_1147528/clarityne
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-12/clarityne_16-11-2011_avis_ct-11099.pdf
http://www.has-sante.fr/portail/jcms/c_1719377/fr/clarityne
2011
France
French
loratadine
tablets
pharmaceutical solutions
administration, oral
loratadine
anti-allergic agents
histamine H1 antagonists, non-sedating
antipruritics
insurance, health, reimbursement
urticaria
chronic disease
rhinitis, allergic, seasonal
rhinitis, allergic, perennial
evaluation of the transparency committee
---
https://www.ema.europa.eu/medicines/human/EPAR/Aerius
2011
United Kingdom
English
French
syndication feed
Contraindications, Procedure
drug approval
loratadine
loratadine
loratadine
loratadine
loratadine
loratadine
rhinitis, allergic, seasonal
urticaria
histamine H1 antagonists, non-sedating
chronic disease
treatment outcome
drug evaluation
histamine H1 antagonists, non-sedating
histamine H1 antagonists, non-sedating
tablets
administration, oral
adult
adolescent
histamine H1 antagonists, non-sedating
pregnancy
breast feeding
histamine H1 antagonists, non-sedating
histamine H1 antagonists, non-sedating
loratadine
drug evaluation, preclinical
drug labeling
desloratadine
desloratadine
drug evaluation
summary of product characteristics
package leaflet
Contraindications, Drug
---
https://www.ema.europa.eu/medicines/human/EPAR/Azomyr
2011
United Kingdom
English
French
syndication feed
Contraindications, Procedure
urticaria
loratadine
histamine H1 antagonists, non-sedating
loratadine
chronic disease
loratadine
loratadine
loratadine
loratadine
histamine H1 antagonists, non-sedating
histamine H1 antagonists, non-sedating
histamine H1 antagonists, non-sedating
histamine H1 antagonists, non-sedating
adult
loratadine
adolescent
drug interactions
pregnancy
breast feeding
drug approval
drug labeling
treatment outcome
drug evaluation, preclinical
tablets
administration, oral
histamine H1 antagonists, non-sedating
rhinitis, allergic, seasonal
desloratadine
desloratadine
drug evaluation
summary of product characteristics
package leaflet
Contraindications, Drug
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68474421
2009
France
French
summary of product characteristics
package leaflet
loratadine
loratadine
administration, oral
anti-allergic agents
anti-allergic agents
histamine H1 antagonists, non-sedating
histamine H1 antagonists, non-sedating
rhinitis, allergic, seasonal
rhinitis, allergic, perennial
loratadine
adult
adolescent
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68637142
2009
France
French
loratadine
histamine H1 antagonists, non-sedating
summary of product characteristics
package leaflet
---
http://www.lecrat.eu/?s=Loratadine+et+hypospadias
2009
France
drug information
hypospadias
loratadine
hypospadias
---
http://www.lecrat.eu/?s=Loratadine
2009
France
French
loratadine
pregnancy
histamine H1 antagonists, non-sedating
breast feeding
loratadine
drug information
---