Omalizumab - CISMeF

Preferred Label : Omalizumab;

MeSH definition : An anti-IgE, recombinant, humanized monoclonal antibody which specifically binds to the C epsilon3 domain of IMMUNOGLOBULIN E, the site of high-affinity IgE receptor binding. It inhibits the binding of IgE to MAST CELLS and BASOPHILS to reduce the severity of the allergic response and is used in the management of persistent allergic ASTHMA.;

MeSH hyponym : xolair;

MeSH CAS label : Immunoglobulin G, anti-(human immunoglobulin E Fc region)(human-mouse monoclonal E25 clone pSVIE26 gamma-chain), disulfide with human-mouse monoclonal E25 clone pSVIE26 kappa-chain, dimer;

MeSH Related Number : 242138-07-4;

Wikipedia link : https://en.wikipedia.org/wiki/Omalizumab;

Is substance : O;

UNII : 2P471X1Z11;

Details

Origin ID

D000069444;

UMLS CUI

C0966225;

ATC code(s)
- omalizumab [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Omalizumab [Substance BNPC]
- Omalizumab [NCIt concept]
- Omalizumab (substance) [SNOMED CT concept]
Pharmacological action(s)
- anti-allergic agents [MeSH Descriptor]
- anti-asthmatic agents [MeSH Descriptor]
Record concept(s)
- omalizumab [MeSH concept]
- xolair [MeSH concept]
See also inter- (CISMeF)
- Product containing omalizumab (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Omalizumab [NCIt concept]
- Omalizumab [Substance BNPC]
- Omalizumab (substance) [SNOMED CT concept]
- Product containing omalizumab (medicinal product) [SNOMED CT concept]
- omalizumab [ATC Code]
Validated automatic mappings to BTNT
- omalizumab [ATC Code]

Keyword's position in hierarchy(ies) :

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