histamine H1 antagonists, non-sedating

Preferred Label : histamine H1 antagonists, non-sedating;

MeSH definition : A class of non-sedating drugs that bind to but do not activate histamine receptors (DRUG INVERSE AGONISM), thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment.;

MeSH synonym : second generation antihistamines; second generation h1 antagonists; h1 antihistamines, non-sedating; h1 antihistamines, non sedating; non-sedating h1 antihistamines; antihistamines, second generation; histamine H1 antagonists, non sedating; Second Generation Antihistamine; Antihistamine, Second Generation; Generation Antihistamine, Second; Second Generation H1 Antagonist;

MeSH hyponym : third generation H1 antagonists; Third Generation H1 Antagonist;

Wikipedia link : https://en.wikipedia.org/wiki/Second generation antihistamines;

Is substance : O;

action pharmacologique : O;

Details

Origin ID

D039563;

UMLS CUI

C1136312;

ATC code(s)
- acrivastine [ATC Code]
- fexofenadine [ATC Code]
- loratadine [ATC Code]
- mizolastine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Second-generation antihistamine [ICD-11 Extension code]
Manual NTBT mappings (CISMeF)
- Non-sedating antihistamine (substance) [Inactive SNOMED CT concept]
Record concept(s)
- histamine H1 antagonists, Non-Sedating [MeSH concept]
- third generation H1 antagonists [MeSH concept]
See also
- anti-allergic agents [MeSH Descriptor]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
Substance(s)
- Olopatadine Hydrochloride [MeSH Descriptor]
- acrivastine [MeSH Supplementary Concept]
- astemizole [MeSH Descriptor]
- azelastine [MeSH Supplementary Concept]
- cetirizine [MeSH Descriptor]
- desloratadine [MeSH Supplementary Concept]
- fexofenadine [MeSH Supplementary Concept]
- levocabastine [MeSH Supplementary Concept]
- levocetirizine [MeSH Supplementary Concept]
- loratadine [MeSH Descriptor]
- mizolastine [MeSH Supplementary Concept]
- terfenadine [MeSH Descriptor]
UMLS correspondences (same concept)
- Non-sedating antihistamine (product) [Inactive SNOMED CT concept]
- Non-sedating antihistamine (substance) [Inactive SNOMED CT concept]
Validated automatic mappings to NTBT
- Non-sedating antihistamine (product) [Inactive SNOMED CT concept]

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