cyclosporine - CISMeF

Preferred Label : cyclosporine;

MeSH definition : A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).;

MeSH synonym : ciclosporin; cyclosporin; cyclosporine a; Cyclosporin A;

CISMeF synonym : restasis; neoral, sandimmun;

MeSH hyponym : CsA-Neoral; OL 27-400; sandimmune; neoral; sandimmun neoral; CyA-NOF; CyA NOF; Sandimmun; CsA Neoral; CsANeoral; OL 27 400; OL 27400;

MeSH CAS label : cyclosporin a;

MeSH Related Number : 59865-13-3 (Cyclosporine);

Registry Number MeSH : 59865-13-3;

MeSH annotation : a specific drug: do not confuse with CYCLOSPORINS;

Wikipedia link : https://en.wikipedia.org/wiki/Ciclosporin;

Is substance : O;

UNII : 83HN0GTJ6D;

InChIKey : PMATZTZNYRCHOR-CGLBZJNRSA-N;

Details

Origin ID

D016572;

UMLS CUI

C0010592;

ATC code(s)
- ciclosporin [ATC Code]
- ciclosporin [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Cyclosporin poisoning (disorder) [SNOMED CT concept]
- Cyclosporine measurement (procedure) [SNOMED CT concept]
- cyclosporine [Substance BNPC]
Currated CISMeF NLP mapping
- Ciclosporin [ICD-11 Extension code]
- Ciclosporin (substance) [SNOMED CT concept]
- Cyclosporine [NCIt concept]
- cycloSPORINE [LOINC component]
- cyclosporine [SNOMED Notion]
- cyclosporine [International Nonproprietary Name]
Exact mapping(s) to DCI
- cyclosporine [International Nonproprietary Name]
False automatic mappings
- Chondrosarcoma [MedDRA Preferred Term]
- chondrosarcoma, nos [SNOMED Notion]
Manual BTNT mappings - CISMeF
- Allergy to ciclosporin (finding) [SNOMED CT concept]
- Chronic cyclosporin A nephrotoxicity (disorder) [SNOMED CT concept]
- Nephropathy caused by ciclosporin (disorder) [SNOMED CT concept]
Pharmacological action(s)
- Calcineurin Inhibitors [MeSH Descriptor]
- antifungal agents [MeSH Descriptor]
- antirheumatic agents [MeSH Descriptor]
- dermatologic agents [MeSH Descriptor]
- immunosuppressive agents [MeSH Descriptor]
Record concept(s)
- CsA-Neoral [MeSH concept]
- OL 27-400 [MeSH concept]
- cyclosporine [MeSH concept]
- neoral [MeSH concept]
- sandimmun neoral [MeSH concept]
- sandimmune [MeSH concept]
Related MeSH Supplementary Concept(s)
- (5-hydroxynorvaline)-2-cyclosporin [MeSH Supplementary Concept]
- (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine [MeSH Supplementary Concept]
- (melle-4)cyclosporin [MeSH Supplementary Concept]
- AM 19 [MeSH Supplementary Concept]
- FR 901459 [MeSH Supplementary Concept]
- M1 cyclosporin metabolite [MeSH Supplementary Concept]
- N-methyl-valyl-4-cyclosporin A [MeSH Supplementary Concept]
- SDZ 211-811 [MeSH Supplementary Concept]
- alisporivir [MeSH Supplementary Concept]
- cyclosporin 29 [MeSH Supplementary Concept]
- cyclosporin G [MeSH Supplementary Concept]
- cyclosporin H [MeSH Supplementary Concept]
- iminoral [MeSH Supplementary Concept]
- voclosporin [MeSH Supplementary Concept]
Related MeSH term(s)
- cyclosporins [MeSH Descriptor]
See also (suggested by CISMeF)
- cyclosporins [MeSH Descriptor]
See also inter- (CISMeF)
- Product containing ciclosporin (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Ciclosporin [ICD-11 Extension code]
- Ciclosporin (substance) [SNOMED CT concept]
- Cyclosporine [NCIt concept]
- Product containing ciclosporin (medicinal product) [SNOMED CT concept]
- ciclosporin [ATC Code]
- ciclosporin [ATC Code]
- cycloSPORINE [LOINC component]
- cyclosporine [SNOMED Notion]
Validated automatic mappings to BTNT
- ciclosporin [ATC Code]
- ciclosporin [ATC Code]
- cycloSPORINE.monoclonal [LOINC component]

Keyword's position in hierarchy(ies) :

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