Preferred Label : granulocyte-macrophage colony-stimulating factor;

MeSH definition : An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.;

MeSH synonym : cell-stimulating factor, histamine-producing; colony stimulating factor, granulocyte macrophage; csf-2; tc-gm-csf; tumor cell human gm colony stimulating factor; tumor-cell human gm colony-stimulating factor; gm-csf; histamine-producing cell-stimulating factor; histamine producing cell stimulating factor; colony-stimulating factor, granulocyte-macrophage; csf-gm; granulocyte macrophage colony stimulating factor;

MeSH CAS label : colony-stimulating factor 2;

Registry Number MeSH : 83869-56-1;

MeSH annotation : DF: GMCSF;

Wikipedia link : https://en.wikipedia.org/wiki/Granulocyte macrophage colony stimulating factor;

Is substance : O;

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An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.

http://www.cochrane.org/fr/CD004139
2012
United Kingdom
France
French
french abstract
meta-analysis
child
treatment outcome
granulocyte-macrophage colony-stimulating factor
neutropenia
precursor b-cell lymphoblastic leukemia-lymphoma
antineoplastic agents
neutropenia
Febrile neutropenia
fever
granulocyte colony-stimulating factor
fever
Chemotherapy-Induced febrile neutropenia

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http://www.cochrane.org/fr/CD008538
2011
false
true
false
United Kingdom
France
treatment outcome
review of literature
french abstract
crohn disease
sargramostim
remission induction
granulocyte-macrophage colony-stimulating factor

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28/04/2025


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