Preferred Label : granulocyte colony-stimulating factor;

MeSH definition : A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.;

MeSH synonym : g-csf; Factor, Granulocyte Colony-Stimulating; Granulocyte Colony Stimulating Factor; Myeloid Growth Factor; Factor, Myeloid Growth; Growth Factor, Myeloid; Colony-Stimulating Factor, Granulocyte; Colony Stimulating Factor, Granulocyte;

MeSH CAS label : colony-stimulating factor, granulocyte;

Registry Number MeSH : 143011-72-7;

MeSH annotation : DF: GCSF;

Wikipedia link : https://en.wikipedia.org/wiki/Granulocyte colony-stimulating factor;

Is substance : O;

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A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.

https://www.has-sante.fr/jcms/p_3434163/fr/lonquex-lipegfilgrastim-facteur-de-croissance-granulocytaire
2023
false
false
false
France
treatment outcome
insurance, health, reimbursement
lipegfilgrastim
adult
child
adolescent
Chemotherapy-Induced febrile neutropenia
Chemotherapy-Induced febrile neutropenia
evaluation of the transparency committee
granulocyte colony-stimulating factor
lipegfilgrastim

---
https://www.srlf.org/article/y-t-il-alternative-therapeutique-transplantation-hepatique-cas-dhepatite-alcoolique-aigue-0
2020
false
false
false
France
acute disease
hepatitis, alcoholic
granulocyte colony-stimulating factor
adult
Lille model
survival analysis
Child-Pugh score (assessment scale)
glucocorticoids
critical appraisal or critical reading
liver transplantation
hepatitis, alcoholic
drug resistance to corticoids
acute alcoholic liver disease

---
https://www.ema.europa.eu/en/medicines/human/EPAR/nyvepria
2020
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
pegfilgrastim
pegfilgrastim
pegfilgrastim
biosimilar pharmaceuticals
Chemotherapy-Induced febrile neutropenia
Chemotherapy induced neutropenia
injections, subcutaneous
product surveillance, postmarketing
adult
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.has-sante.fr/jcms/p_3191905/fr/grasustek
2020
false
false
false
France
biosimilar pharmaceuticals
pegfilgrastim
pegfilgrastim
insurance, health, reimbursement
treatment outcome
injections, subcutaneous
adult
Chemotherapy-Induced febrile neutropenia
Chemotherapy-Induced febrile neutropenia
evaluation of the transparency committee
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.has-sante.fr/jcms/p_3181643/fr/cegfila
2020
false
false
false
France
biosimilar pharmaceuticals
pegfilgrastim
adult
treatment outcome
insurance, health, reimbursement
Chemotherapy-Induced febrile neutropenia
Chemotherapy-Induced febrile neutropenia
pegfilgrastim
evaluation of the transparency committee
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.has-sante.fr/jcms/p_3135363/fr/pelgraz
2019
false
false
false
France
French
pegfilgrastim
evaluation of the transparency committee
Injection moulding
Solutions
devices
injections
solutions
Set, Psychology
solution, nos
injection, nos
device, nos
Intraspinal abscess
equipment and supplies
solutions
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.ema.europa.eu/en/medicines/human/EPAR/udenyca
2019
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
pegfilgrastim
pegfilgrastim
biosimilar pharmaceuticals
neutropenia
Chemotherapy-Induced febrile neutropenia
Chemotherapy induced neutropenia
neutropenia
antineoplastic agents
injections, subcutaneous
pegfilgrastim
product surveillance, postmarketing
adult
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.has-sante.fr/jcms/p_3108945/fr/lonquex
2019
false
false
false
France
insurance, health, reimbursement
treatment outcome
lipegfilgrastim
injections, subcutaneous
lipegfilgrastim
adult
Chemotherapy-Induced febrile neutropenia
neutropenia
evaluation of the transparency committee
pegfilgrastim
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.has-sante.fr/jcms/p_3106643/fr/fulphila
2019
false
false
false
France
pegfilgrastim
treatment outcome
pegfilgrastim
adult
Chemotherapy-Induced febrile neutropenia
biosimilar pharmaceuticals
evaluation of the transparency committee
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.ema.europa.eu/en/medicines/human/EPAR/grasustek
2019
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
pegfilgrastim
pegfilgrastim
pegfilgrastim
Chemotherapy-Induced febrile neutropenia
leukemia, myelogenous, chronic, bcr-abl positive
myelodysplastic syndromes
Chemotherapy induced neutropenia
neutropenia
neutropenia
antineoplastic agents
injections, subcutaneous
product surveillance, postmarketing
adult
drug interactions
pregnancy
breast feeding
biosimilar pharmaceuticals
drug evaluation, preclinical
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.ema.europa.eu/en/medicines/human/EPAR/pegfilgrastim-mundipharma
2019
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
pegfilgrastim
pegfilgrastim
Chemotherapy-Induced febrile neutropenia
Chemotherapy induced neutropenia
neutropenia
neutropenia
antineoplastic agents
biosimilar pharmaceuticals
injections, subcutaneous
pegfilgrastim
product surveillance, postmarketing
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.has-sante.fr/portail/jcms/c_2892924/fr/ziextenzo
2019
false
false
false
France
French
pegfilgrastim
treatment outcome
biosimilar pharmaceuticals
evaluation of the transparency committee
pegfilgrastim
Chemotherapy-Induced febrile neutropenia
Chemotherapy induced neutropenia
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.ema.europa.eu/en/medicines/human/EPAR/ziextenzo
2019
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
biosimilar pharmaceuticals
pegfilgrastim
pegfilgrastim
pegfilgrastim
neutropenia
neutropenia
antineoplastic agents
Chemotherapy-Induced febrile neutropenia
injections, subcutaneous
product surveillance, postmarketing
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.has-sante.fr/portail/jcms/c_2900187/fr/pelmeg
2019
false
false
false
France
French
treatment outcome
Chemotherapy-Induced febrile neutropenia
biosimilar pharmaceuticals
pegfilgrastim
injections, subcutaneous
evaluation of the transparency committee
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailTwo.php?lang=fr&linkID=SBD00432
2019
false
false
false
Canada
French
drug information
drug approval
canada
treatment outcome
injections, subcutaneous
pegfilgrastim
pegfilgrastim
pegfilgrastim
Chemotherapy-Induced febrile neutropenia
adult
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.has-sante.fr/portail/jcms/c_2888499/fr/pelgraz
2018
false
false
false
France
treatment outcome
pegfilgrastim
pegfilgrastim
biosimilar pharmaceuticals
Chemotherapy-Induced febrile neutropenia
injections, subcutaneous
pegfilgrastim
adult
insurance, health, reimbursement
evaluation of the transparency committee
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.ema.europa.eu/en/medicines/human/EPAR/pelmeg
2018
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
Chemotherapy-Induced febrile neutropenia
drug approval
europe
biosimilar pharmaceuticals
pegfilgrastim
pegfilgrastim
injections, subcutaneous
product surveillance, postmarketing
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
Chemotherapy induced neutropenia
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.ema.europa.eu/en/medicines/human/EPAR/fulphila-0
2018
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
pegfilgrastim
pegfilgrastim
pegfilgrastim
biosimilar pharmaceuticals
antineoplastic agents
neutropenia
neutropenia
injections, subcutaneous
product surveillance, postmarketing
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
Chemotherapy-Induced febrile neutropenia
Chemotherapy induced neutropenia
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.ema.europa.eu/en/medicines/human/EPAR/pelgraz
2018
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
pegfilgrastim
pegfilgrastim
biosimilar pharmaceuticals
pegfilgrastim
neutropenia
Chemotherapy-Induced febrile neutropenia
neutropenia
antineoplastic agents
injections, subcutaneous
product surveillance, postmarketing
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
https://www.inesss.qc.ca/index.php?id=72&DemandePluginController%5Buid%5D=4526&DemandePluginController%5Bonglet%5D=2&DemandePluginController%5BbackUrl%5D=%252Findex.php%253Fid%253D72%2526no_cache%253D1%2526DemandePluginController%25255Buid%25255D%253D4469%2526DemandePluginController%25255Bonglet%25255D%253D2%2526DemandePluginController%25255BbackUrl%25255D%253D%2525252Findex.php%2525253Fid%2525253D72%25252526no_cache%2525253D1%25252526DemandePluginController%252525255Buid%252525255D%2525253D4496%25252526DemandePluginController%252525255Bonglet%252525255D%2525253D2&cHash=5e70eb8df42c4346c411ee357a44aff6
2018
false
false
false
Canada
French
drug evaluation
pegfilgrastim
pegfilgrastim
granulocyte colony-stimulating factor
recombinant proteins

---
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailTwo.php?lang=fr&linkID=SBD00396
2018
false
true
false
Canada
French
English
drug information
pegfilgrastim
pegfilgrastim
granulocyte colony-stimulating factor
recombinant proteins
Filgrastim
polyethylene glycols

---
http://www.cochrane.org/fr/CD010615/lajout-de-plerixafor-aux-facteurs-de-stimulation-des-colonies-de-granulocytes-pour-la-mobilisation
2015
false
false
false
France
United Kingdom
French
review of literature
involved
mobilization, nos
hematopoietic stem cell mobilization
Cell
colony-forming unit, nos
lymphoma
Myeloma
malignant
stimulator, nos
autograft
Myeloma
malignant lymphoma, nos
granulocyte colony-stimulating factor
postman
acute myeloid leukemia
transplantation, autologous
large intestine, nos
persons
plerixafor
vision, ocular
Malignant lymphoma
multiple myeloma
hematopoietic stem cell transplantation
multiple myeloma
plerixafor
heterocyclic compounds

---
http://www.has-sante.fr/portail/jcms/c_2570608/fr/neulasta
http://www.has-sante.fr/portail/jcms/c_697297/neulasta
http://www.has-sante.fr/portail/jcms/c_399819/fr/neulasta-6-mg-solution-injectable-boite-de-1-seringue-de-verre-preremplie
2015
false
true
false
false
France
French
evaluation of the transparency committee
pegfilgrastim
pegfilgrastim
injections, subcutaneous
insurance, health, reimbursement
treatment outcome
Chemotherapy-Induced febrile neutropenia
granulocyte colony-stimulating factor
recombinant proteins

---
https://www.ema.europa.eu/medicines/human/EPAR/Ristempa
2015
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
pegfilgrastim
pegfilgrastim
pegfilgrastim
drug approval
europe
Chemotherapy-Induced febrile neutropenia
Chemotherapy-Induced febrile neutropenia
injections, subcutaneous
Injectable Solution Dosage Form
Prefilled Syringe Dosage Form
adult
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
Chemotherapy induced neutropenia
recombinant proteins
granulocyte colony-stimulating factor
recombinant proteins
granulocyte colony-stimulating factor

---
http://www.has-sante.fr/portail/jcms/c_1745375/fr/lonquex-lipegfilgrastim-facteur-de-croissance-granulocytaire
2014
false
false
false
France
French
guidelines for drug use
evaluation of the transparency committee
lipegfilgrastim
lipegfilgrastim
lipegfilgrastim
injections, subcutaneous
neutropenia
Chemotherapy-Induced febrile neutropenia
adult
treatment outcome
insurance, health, reimbursement
pegfilgrastim
pegfilgrastim
recombinant proteins
granulocyte colony-stimulating factor
recombinant proteins
granulocyte colony-stimulating factor

---
http://www.cochrane.org/fr/CD008844
2013
United Kingdom
France
French
review of literature
myocardial infarction
treatment outcome
granulocyte colony-stimulating factor
french abstract

---
http://www.cochrane.org/fr/CD006810
2013
United Kingdom
France
French
diabetes complications
french abstract
meta-analysis
diabetic foot
treatment outcome
granulocyte colony-stimulating factor
Infections

---
http://www.cochrane.org/fr/CD004139
2012
United Kingdom
France
French
french abstract
meta-analysis
child
treatment outcome
granulocyte-macrophage colony-stimulating factor
neutropenia
precursor b-cell lymphoblastic leukemia-lymphoma
antineoplastic agents
neutropenia
Febrile neutropenia
fever
granulocyte colony-stimulating factor
fever
Chemotherapy-Induced febrile neutropenia

---
http://www.has-sante.fr/portail/jcms/c_682852/granocyte-sortie-de-la-reserve-hospitaliere-decret-2004
http://www.has-sante.fr/portail/jcms/c_683854/granocyte-srh
2008
France
French
granulocyte colony-stimulating factor
recombinant proteins
adjuvants, immunologic
neutropenia
lenograstim
granulocyte colony-stimulating factor
recombinant proteins
guidelines for drug use
Lenograstim

---
http://www.meddispar.fr/medicaments/3497567
2008
France
French
granulocyte colony-stimulating factor
recombinant proteins
drug prescriptions
legislation, drug
injections
lenograstim
drug information
Lenograstim

---
http://www.meddispar.fr/medicaments/3497610
2008
France
French
granulocyte colony-stimulating factor
recombinant proteins
injections
drug prescriptions
legislation, drug
lenograstim
drug information
Lenograstim

---
https://www.cadth.ca/sites/default/files/pdf/H0473_Granulocyte_Colony_Stimulating_Factor_tr_f.pdf
https://www.cadth.ca/fr/le-facteur-stimulant-les-colonies-de-granulocytes-g-csf-dans-la-neutropenie-due-la-chimiotherapie
2008
true
Canada
French
neutropenia
granulocyte colony-stimulating factor
antineoplastic agents
granulocyte colony-stimulating factor
colony stimulating factors
evaluation studies
drug evaluation

---
https://hemato.chu-limoges.fr/hematolim/Portals/0/Info_patient/soins%20de%20support/facteurs%20de%20croissance/livret_EPO_2009.pdf
2006
false
true
false
France
popular works
erythropoietin
granulocyte colony-stimulating factor

---
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24/04/2025


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