Preferred Label : plerixafor;

MeSH note : a bicyclam derivate, highly potent & selective inhibitor of HIV-1 & HIV-2; partial structure given in first source;

CISMeF synonym : 1,1'-(1,4-phenylenebis-(methylene))-bis-1,4,8,11-tetraazacyclotetradecane octahydrochloride dihydrate; bicyclam; AMD 3329; JM-3100; plerixafor octahydrochloride;

MeSH synonym : 1,1'-(1,4-phenylenebis-(methylene))-bis-1,4,8,11-tetraazacyclotetradecane;

MeSH hyponym : JM3100; 1,1'-(1,4-phenylenebis(methylene))bis(1,4,8,11-tetraazacyclotetradecane)octahydrochloride dihydrate; AMD3100; AMD-3100; mezobil; mozobil; JM 3100; AMD 3100; plerixafor hydrochloride; RPA bicyclam; AMD-3329;

Related MeSH term : AMD-3329;

MeSH Related Number : 3EUZ070LLN; 155148-31-5 (plerixafor octahydrochloride); OD49913540; S79I522MQB;

Registry Number MeSH : 155148-31-5; OD49913540;

Is substance : O;

UNII : S915P5499N;

Details


Main resources

You can consult :


https://www.ema.europa.eu/en/medicines/human/EPAR/plerixafor-accord
2023
false
false
false
Netherlands
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
plerixafor
plerixafor
drug approval
europe
plerixafor
drugs, generic
adult
infant
child
adolescent
aged
hematopoietic stem cell mobilization
lymphoma
multiple myeloma
injections, subcutaneous
hematopoietic stem cell transplantation
pregnancy
breast feeding
drug evaluation, preclinical

---
https://www.has-sante.fr/jcms/p_3164681
2020
France
evaluation of the transparency committee
plerixafor
plerixafor

---
http://www.cochrane.org/fr/CD010615/lajout-de-plerixafor-aux-facteurs-de-stimulation-des-colonies-de-granulocytes-pour-la-mobilisation
2015
false
false
false
France
United Kingdom
French
review of literature
involved
mobilization, nos
hematopoietic stem cell mobilization
Cell
colony-forming unit, nos
lymphoma
Myeloma
malignant
stimulator, nos
autograft
Myeloma
malignant lymphoma, nos
granulocyte colony-stimulating factor
postman
acute myeloid leukemia
transplantation, autologous
large intestine, nos
persons
plerixafor
vision, ocular
Malignant lymphoma
multiple myeloma
hematopoietic stem cell transplantation
multiple myeloma
plerixafor
heterocyclic compounds

---
http://www.has-sante.fr/portail/jcms/c_2006720/fr/mozobil
http://www.has-sante.fr/portail/jcms/c_938999/mozobil-plerixafor-antagoniste-du-cxcr4
2014
false
France
French
Autologous Hematopoietic Stem Cell Transplantation
plerixafor
heterocyclic compounds
plerixafor
drug therapy, combination
orphan drug production
receptors, cxcr4
hematopoietic stem cell mobilization
plerixafor
heterocyclic compounds
injections, subcutaneous
transplantation, autologous
lymphoma
multiple myeloma
hematopoietic stem cell transplantation
treatment outcome
heterocyclic compounds
plerixafor
plerixafor
evaluation of the transparency committee

---
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailOne.php?lang=fr&linkID=SBD00095
2012
false
false
false
Canada
plerixafor
plerixafor
Product containing precisely plerixafor 20 milligram/1 milliliter conventional release solution for injection (clinical drug)
drug information
plerixafor
heterocyclic compounds

---
https://www.ema.europa.eu/medicines/human/EPAR/Mozobil
2012
United Kingdom
French
English
syndication feed
drug interactions
pregnancy
breast feeding
treatment outcome
multiple myeloma
injections, subcutaneous
drug approval
drug labeling
lymphoma, Non-Hodgkin
heterocyclic compounds
orphan drug production
heterocyclic compounds
plerixafor
plerixafor
pharmaceutical solutions
transplantation, autologous
hematopoietic stem cell transplantation
hematopoietic stem cell mobilization
hematopoietic stem cells
receptors, cxcr4
plerixafor
drug evaluation, preclinical
plerixafor
plerixafor
summary of product characteristics
package leaflet
drug evaluation

---
http://www.has-sante.fr/portail/jcms/c_903961/mozobil
2009
true
France
French
guidelines for drug use
plerixafor
heterocyclic compounds
plerixafor
drug therapy, combination
orphan drug production
receptors, cxcr4
hematopoietic stem cell mobilization
plerixafor
heterocyclic compounds
injections, subcutaneous
transplantation, autologous
lymphoma
multiple myeloma
hematopoietic stem cell transplantation
treatment outcome
heterocyclic compounds
plerixafor
plerixafor
evaluation of the transparency committee

---
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02/06/2024


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