CD4 Antigens - CISMeF

Preferred Label : CD4 Antigens;

MeSH definition : 55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.; 55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. They are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. T4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.;

MeSH synonym : cd4 receptor, surface; cd4 receptors; cd4 receptors, surface; receptors, cd4; t-cell t4 antigens; surface cd4 receptor; antigens, t-cell t4; t4 antigens, t-cell; receptors, surface cd4; surface cd4 receptors; t4 antigens, t cell; cd4 antigen; antigen, cd4; cd4 molecule; Antigens, CD4; CD4 Receptor; Receptor, CD4;

MeSH annotation : for hematodermic CD4/CD56 neoplasm use LYMPHOMA, NON-HODGKIN;

Wikipedia link : https://en.wikipedia.org/wiki/Cd4 antigens;

Is substance : O;

Details

Origin ID

D015704;

UMLS CUI

C0003323;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- CD4 Expressing Cell Count [NCIt concept]
- CD4 Gene [NCIt concept]
- CD4 cells [LOINC component]
- CD4 molecule [OBI concept]
- CD4 molecule [HGNC gene]
- CHD4 wt Allele [NCIt concept]
- Cd4 antigen [OMIM gene]
- Chromodomain-Helicase-DNA-Binding Protein 4 [NCIt concept]
Currated CISMeF NLP mapping
- CD4 [LOINC component]
- CD4 Ag [LOINC component]
- Lymphocyte antigen CD4 (substance) [SNOMED CT concept]
- lymphocyte antigen cd4 [SNOMED Notion]
Indexing information
- 13B8-2 monoclonal antibody [MeSH Supplementary Concept]
- CD4 silencer, african green monkey [MeSH Supplementary Concept]
- CD4-Pseudomonas toxin [MeSH Supplementary Concept]
- OKT4A monoclonal antibody [MeSH Supplementary Concept]
- OX-38 monoclonal antibody [MeSH Supplementary Concept]
- RIB 5-2 monoclonal antibody [MeSH Supplementary Concept]
- S-benzyl-CD4 (83-94) peptide [MeSH Supplementary Concept]
- clenoliximab [MeSH Supplementary Concept]
- keliximab [MeSH Supplementary Concept]
- vasoactive intestinal peptide (1-12) [MeSH Supplementary Concept]
Record concept(s)
- CD4 Antigens [MeSH concept]
Related MeSH Supplementary Concept(s)
- CD4 (76-94) [MeSH Supplementary Concept]
- CD4 (81-92) [MeSH Supplementary Concept]
- CD4 S1 peptide [MeSH Supplementary Concept]
- CD4-IgG1 hinge fusion protein, recombinant [MeSH Supplementary Concept]
- CD4-ricin A chain conjugate [MeSH Supplementary Concept]
- CDR3.AME(82-89) [MeSH Supplementary Concept]
- DAB389CD4 [MeSH Supplementary Concept]
- recombinant soluble CD4 [MeSH Supplementary Concept]
See also
- CD4-CD8 ratio [MeSH Descriptor]
- HIV envelope protein gp120 [MeSH Descriptor]
- Immunoglobulin Domains [MeSH Descriptor]
- cd4-positive t-lymphocytes [MeSH Descriptor]
See also inter- (CISMeF)
- T-Cell Surface Glycoprotein CD4 [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- CD4 [LOINC component]
- CD4 Ag [LOINC component]
- Lymphocyte antigen CD4 (substance) [SNOMED CT concept]
- lymphocyte antigen cd4 [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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