MeSH definition : A critical subpopulation of T-lymphocytes involved in the induction of most immunological
functions. The HIV virus has selective tropism for the T4 cell which expresses the
CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound
immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.;
MeSH annotation : subpopulations: index specifics if available or coordinate CD4-POSITIVE T-LYMPHOCYTES
with T-LYMPHOCYTE SUBSETS; count: coordinate IM with CD4 LYMPHOCYTE COUNT (NIM);
A critical subpopulation of T-lymphocytes involved in the induction of most immunological
functions. The HIV virus has selective tropism for the T4 cell which expresses the
CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound
immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.