spironolactone

Preferred Label : spironolactone;

MeSH definition : A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827);

MeSH synonym : veroshpiron; verospirone; spirolactone;

CISMeF synonym : pharmacia brand of spironolactone; pharmacia spain brand of spironolactone; alphapharm brand of spironolactone; betapharm brand of spironolactone; wörwag brand of spironolactone; alpharma brand of spironolactone; dexo brand of spironolactone; ashbourne brand of spironolactone; roche brand of spironolactone; searle brand of spironolactone; pfizer brand of spironolactone; azupharma brand of spironolactone; merck dura brand of spironolactone; alter brand of spironolactone; mundogen brand of spironolactone; Mayoly-Spindler brand of spironolactone; jenapharm brand of spironolactone; novopharm brand of spironolactone; cardel brand of spironolactone; pharmafrid brand of spironolactone; ct-Arzneimittel brand of spironolactone; ct arzneimittel brand of spironolactone; generosan brand of spironolactone; hormosan brand of spironolactone;

MeSH hyponym : spirospare; espironolactona alter; jenaspiron; spironone; aquareduct; Novo-Spiroton; frumikal; espironolactona mundogen; aldactone A; SC-9420; duraspiron; verospiron; spiro von ct; spirolang; Spirono-Isis; practon; spirobeta; spirogamma; spiractin; flumach; aldactone; spiro L.U.T.; Spirono Isis; Novo Spiroton; NovoSpiroton; SC 9420; SC9420; Ct, Spiro Von; Von Ct, Spiro;

MeSH CAS label : Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, gamma-lactone, (7alpha,17alpha)-;

MeSH Related Number : 52-01-7 (Spironolactone);

Registry Number MeSH : 52-01-7;

Wikipedia link : https://en.wikipedia.org/wiki/Spironolactone;

Codes EINECS : 200-133-6;

Is substance : O;

UNII : 27O7W4T232;

InChIKey : LXMSZDCAJNLERA-ZHYRCANASA-N;

Details

Origin ID

D013148;

UMLS CUI

C0037982;

ATC code(s)
- spironolactone [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Spironolactone adverse reaction (disorder) [SNOMED CT concept]
- Spironolactone measurement (procedure) [SNOMED CT concept]
- spironolactone [Substance BNPC]
Currated CISMeF NLP mapping
- Spironolactone [ICD-11 Extension code]
- Spironolactone [LOINC component]
- Spironolactone [ICHI extension code]
- Spironolactone [SMS substance]
- Spironolactone [NCIt concept]
- Spironolactone (substance) [SNOMED CT concept]
- spironolactone [SNOMED Notion]
Fils d'après SNOMED CT
- mineralocorticoid receptor antagonists [MeSH Descriptor]
Pharmacological action(s)
- diuretics [MeSH Descriptor]
- mineralocorticoid receptor antagonists [MeSH Descriptor]
Record concept(s)
- Novo-Spiroton [MeSH concept]
- SC-9420 [MeSH concept]
- Spirono-Isis [MeSH concept]
- aldactone [MeSH concept]
- aldactone A [MeSH concept]
- aquareduct [MeSH concept]
- duraspiron [MeSH concept]
- espironolactona alter [MeSH concept]
- espironolactona mundogen [MeSH concept]
- flumach [MeSH concept]
- frumikal [MeSH concept]
- jenaspiron [MeSH concept]
- practon [MeSH concept]
- spiractin [MeSH concept]
- spiro L.U.T. [MeSH concept]
- spiro von ct [MeSH concept]
- spirobeta [MeSH concept]
- spirogamma [MeSH concept]
- spirolang [MeSH concept]
- spironolactone [MeSH concept]
- spironone [MeSH concept]
- spirospare [MeSH concept]
- verospiron [MeSH concept]
Related MeSH Supplementary Concept(s)
- 3-(3-oxo-7 alpha-methylsulfonyl-6 beta,17 beta- dihydroxy-4-androsten-17 alpha-yl)propionic acid gamma-lactone [MeSH Supplementary Concept]
- 6,6-ethylene-15,16-methylene-3-oxo-17-pregn-4-ene-2,17-carbolactone [MeSH Supplementary Concept]
- 6,7-epoxycanrenone [MeSH Supplementary Concept]
- 6-hydroxy-7-thiomethylspirolactone [MeSH Supplementary Concept]
- 7 alpha-thiospironolactone [MeSH Supplementary Concept]
- 7-propyl spirolactone [MeSH Supplementary Concept]
- 7-thiomethylspirolactone [MeSH Supplementary Concept]
- 7alpha-(methylthio)spironolactone S-oxide [MeSH Supplementary Concept]
- 8-(3-(4-fluorobenzoyl)propyl)-1-methyl-1,3,8-triazaspiro(4,5)decan-4-one [MeSH Supplementary Concept]
- 8-(3-(4-iodobenzoyl)propyl)-1-methyl-1,3,8-triazaspiro(4,5)decan-4-one [MeSH Supplementary Concept]
- RU 28318 [MeSH Supplementary Concept]
- SC 25152 [MeSH Supplementary Concept]
- SC 26304 [MeSH Supplementary Concept]
- SC 30822 [MeSH Supplementary Concept]
- SC 8109 [MeSH Supplementary Concept]
- SC70303 [MeSH Supplementary Concept]
- ZK 91587 [MeSH Supplementary Concept]
- ZK 97894 [MeSH Supplementary Concept]
- bupranolol, spironolactone drug combination [MeSH Supplementary Concept]
- buthiazide, spironolactone drug combination [MeSH Supplementary Concept]
- dihydroxy-6,7-dihydrocanrenone [MeSH Supplementary Concept]
- epoxymexrenone [MeSH Supplementary Concept]
- lasilacton [MeSH Supplementary Concept]
- mespirenone [MeSH Supplementary Concept]
- naphthospironone [MeSH Supplementary Concept]
- prorenoate potassium [MeSH Supplementary Concept]
- prorenone [MeSH Supplementary Concept]
- spironolactone, althiazide drug combination [MeSH Supplementary Concept]
- spironolactone-beta-cyclodextrin complex [MeSH Supplementary Concept]
- spiroprop [MeSH Supplementary Concept]
- yaoshanenolide A [MeSH Supplementary Concept]
- yaoshanenolide B [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Aldactone [ICD-11 Extension code]
- Product containing spironolactone (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing spironolactone (medicinal product) [SNOMED CT concept]
- Spironolactone [ICD-11 Extension code]
- Spironolactone [NCIt concept]
- Spironolactone [LOINC component]
- Spironolactone (substance) [SNOMED CT concept]
- spironolactone [ATC Code]
- spironolactone [Substance BNPC]
- spironolactone [SNOMED Notion]
Validated automatic mappings to BTNT
- spironolactone [ATC Code]

Keyword's position in hierarchy(ies) :

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