sodium potassium chloride symporter inhibitors

Preferred Label : sodium potassium chloride symporter inhibitors;

MeSH definition : Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA.;

MeSH synonym : na-k-cl symporter inhibitors; bumetanide sensitive na-k-cl-transporter inhibitors; inhibitors, na-k-cl symporter; na k cl symporter inhibitors; symporter inhibitors, na-k-cl; sodium potassium chloride cotransporter inhibitors; bumetanide sensitive na k cl transporter inhibitors;

Related MeSH term : loop diuretics; high ceiling diuretics; Diuretics, Loop; Ceiling Diuretics, High; Diuretics, High Ceiling; Loop Diuretic; Diuretic, Loop;

MeSH annotation : coordinate with DIURETICS if pertinent;

Wikipedia link : https://en.wikipedia.org/wiki/Sodium potassium chloride symporter inhibitors;

Is substance : O;

action pharmacologique : O;

Details

Origin ID

D049994;

UMLS CUI

C1563713;

ATC code(s)
- high-ceiling diuretics [ATC Code]
- high-ceiling diuretics and potassium-sparing agents [ATC Code]
- sulfonamides and potassium in combination [ATC Code]
- sulfonamides, plain [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Loop diuretic poisoning (disorder) [SNOMED CT concept]
False automatic mappings
- Poisoning by, adverse effect of and underdosing of loop [high-ceiling] diuretics [ICD-10 Sub-category]
MeSH Descriptor(s) used for indexing
- Sodium-Potassium-Chloride symporters [MeSH Descriptor]
Record concept(s)
- high ceiling diuretics [MeSH concept]
- loop diuretics [MeSH concept]
- sodium potassium chloride symporter inhibitors [MeSH concept]
See also (suggested by CISMeF)
- diuretics [MeSH Descriptor]
See also inter- (CISMeF)
- Loop Diuretic [NCIt concept]
- Loop [high-ceiling] diuretics [ICD-10 Sub-category (who)]
- Loop [high-ceiling] diuretics [ICD-10 Sub-category (who)]
- Loop diuretic (substance) [SNOMED CT concept]
- loop diuretic [SNOMED Notion]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
Substance(s)
- Bumepamine [MeSH Supplementary Concept]
- Torsemide [MeSH Descriptor]
- bumetanide [MeSH Descriptor]
- furosemide [MeSH Descriptor]
- piretanide [MeSH Supplementary Concept]
- tripamide [MeSH Supplementary Concept]

Keyword's position in hierarchy(ies) :

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