Preferred Label : Spironolactone;
NCIt synonyms : SPL;
NCIt related terms : 17-Hydroxy-7alpha-mercapto-3-oxo-17alpha-pregn-4-ene-21-carboxylic Acid, gamma Lactone,
Acetate; Aldactone;
NCIt definition : A synthetic 17-spironolactone corticosteroid with potassium-sparing diuretic, antihypertensive,
and antiandrogen activities.Spironolactone competitively inhibits adrenocortical hormone
aldosterone activity in the distal renal tubules, myocardium, and vasculature. This
agent may inhibit the pathophysiologic effects of aldosterone produced in excess by
various types of malignant and benign tumors.;
UNII : 27O7W4T232;
InChIKey : LXMSZDCAJNLERA-ZHYRCANASA-N;
CAS number : 52-01-7;
Molecule name : SC 9420;
Chemical formula : C24H32O4S;
NSC code : 150399;
ChEBI ID : CHEBI:9241;
Codes from synonyms : NSC0150399; 07605;
Origin ID : C840;
UMLS CUI : C0037982;
Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
