Spironolactone

Preferred Label : Spironolactone;

NCIt synonyms : SPL;

NCIt related terms : 17-Hydroxy-7alpha-mercapto-3-oxo-17alpha-pregn-4-ene-21-carboxylic Acid, gamma Lactone, Acetate; Aldactone;

NCIt definition : A synthetic 17-spironolactone corticosteroid with potassium-sparing diuretic, antihypertensive, and antiandrogen activities.Spironolactone competitively inhibits adrenocortical hormone aldosterone activity in the distal renal tubules, myocardium, and vasculature. This agent may inhibit the pathophysiologic effects of aldosterone produced in excess by various types of malignant and benign tumors.;

UNII : 27O7W4T232;

InChIKey : LXMSZDCAJNLERA-ZHYRCANASA-N;

CAS number : 52-01-7;

Molecule name : SC 9420;

Chemical formula : C24H32O4S;

NSC code : 150399;

ChEBI ID : CHEBI:9241;

Codes from synonyms : NSC0150399; 07605;

Details

Origin ID

C840;

UMLS CUI

C0037982;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing spironolactone (medicinal product) [SNOMED CT concept]
- Spironolactone [ICD-11 Extension code]
- Spironolactone [LOINC component]
- Spironolactone (substance) [SNOMED CT concept]
- spironolactone [ATC Code]
- spironolactone [Substance BNPC]
- spironolactone [MeSH concept]
- spironolactone [MeSH Descriptor]
- spironolactone [SNOMED Notion]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients