myasthenia gravis

Preferred Label : myasthenia gravis;

MeSH definition : A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition. (Adams et al., Principles of Neurology, 6th ed, p1459); A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.;

MeSH hyponym : myasthenia gravis, ocular; myasthenia gravis, generalized; Ocular Myasthenia Gravis; Generalized Myasthenia Gravis; Muscle Specific Receptor Tyrosine Kinase Myasthenia Gravis; Muscle-Specific Tyrosine Kinase Antibody Positive Myasthenia Gravis; Muscle Specific Tyrosine Kinase Antibody Positive Myasthenia Gravis; MuSK MG; MuSK Myasthenia Gravis; Myasthenia Gravis, MuSK; Anti-MuSK Myasthenia Gravis; Anti MuSK Myasthenia Gravis; Myasthenia Gravis, Anti-MuSK;

MeSH annotation : myasthenia unqualified in foreign titles is more often MYASTHENIA GRAVIS than MUSCLE WEAKNESS but check text; congen consider MYASTHENIC SYNDROMES, CONGENITAL or specifics; myasthenia unqualified in foreign titles is more often MYASTHENIA GRAVIS than MUSCLE WEAKNESS but check text; congenital: consider MYASTHENIC SYNDROMES, CONGENITAL or specifics;

Wikipedia link : https://en.wikipedia.org/wiki/Myasthenia gravis;

Details

Origin ID

D009157;

UMLS CUI

C0026896;

Allowable qualifiers
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemically induced [MeSH Qualifier]
- classification [MeSH Qualifier]
- complications [MeSH Qualifier]
- diagnosis [MeSH Qualifier]
- diagnostic imaging [MeSH Qualifier]
- diet therapy [MeSH Qualifier]
- drug therapy [MeSH Qualifier]
- economics [MeSH Qualifier]
- embryology [MeSH Qualifier]
- enzymology [MeSH Qualifier]
- epidemiology [MeSH Qualifier]
- ethnology [MeSH Qualifier]
- etiology [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- microbiology [MeSH Qualifier]
- mortality [MeSH Qualifier]
- nursing [MeSH Qualifier]
- parasitology [MeSH Qualifier]
- pathology [MeSH Qualifier]
- physiopathology [MeSH Qualifier]
- prevention and control [MeSH Qualifier]
- psychology [MeSH Qualifier]
- radiotherapy [MeSH Qualifier]
- rehabilitation [MeSH Qualifier]
- surgery [MeSH Qualifier]
- therapy [MeSH Qualifier]
- urine [MeSH Qualifier]
- veterinary [MeSH Qualifier]
- virology [MeSH Qualifier]
Currated CISMeF NLP mapping
- Myasthenia [HPO term]
- Myasthenia [MedDRA LLT]
- Myasthenia [HRDO Sign]
- Myasthenia Gravis [NCIt concept]
- Myasthenia gravis [PASCAL descriptor]
- Myasthenia gravis [ICD-10 Sub-category]
- Myasthenia gravis [ICD-11 Category]
- Myasthenia gravis [ICD-10 Sub-category (who)]
- Myasthenia gravis [ICD-9 code]
- Myasthenia gravis [OMIM Phenotype]
- Myasthenia gravis [MedDRA Preferred Term]
- Myasthenia gravis [ORDO Disease]
- Myasthenia gravis (disorder) [SNOMED CT concept]
- myasthenia gravis [DO Concept]
- myasthenia gravis [Disease (Nov.)]
- myasthenia gravis [MedlinePlus Topic]
- myasthenia gravis [Blood Transfusion thesaurus concept]
- myasthenia gravis, nos [SNOMED Notion]
DO Cross reference
- myasthenia gravis [DO Concept]
Indexing information
- anti-ryanodine receptor autoantibody [MeSH Supplementary Concept]
- anti-titin autoantibody [MeSH Supplementary Concept]
- myasthenia gravis anti-skeletal muscle antibody [MeSH Supplementary Concept]
Manual NTBT mappings (CISMeF)
- Acquired neuromuscular junction disease [ORDO Disease]
- Autoimmune neurological channelopathy due to an acetylcholine receptor subunits defect [ORDO Disease]
- Sucking/swallowing disorder associated with a neuromuscular disease [ORDO Disease]
MedlinePlus topic(s)
- myasthenia gravis [MedlinePlus Topic]
ORDO relation(s)
- Myasthenia gravis [ORDO Disease]
Record concept(s)
- Muscle-Specific Receptor Tyrosine Kinase Myasthenia Gravis [MeSH concept]
- myasthenia gravis [MeSH concept]
- myasthenia gravis, generalized [MeSH concept]
- myasthenia gravis, ocular [MeSH concept]
Related MeSH Supplementary Concept(s)
- congenital myasthenic syndrome with episodic apnea [MeSH Supplementary Concept]
- myasthenia gravis with thymus hyperplasia [MeSH Supplementary Concept]
- myasthenia, Limb-Girdle, autoimmune [MeSH Supplementary Concept]
See also
- myasthenic syndromes, congenital [MeSH Descriptor]
- thymus hyperplasia [MeSH Descriptor]
See also (suggested by CISMeF)
- lambert-eaton myasthenic syndrome [MeSH Descriptor]
- muscle weakness [MeSH Descriptor]
See also inter- (CISMeF)
- Myasthenia Gravis, CTCAE [NCIt concept]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- Myasthenia Gravis [NCIt concept]
- Myasthenia gravis [MedDRA Preferred Term]
- Myasthenia gravis [ICD-9 code]
- Myasthenia gravis [OMIM Phenotype]
- Myasthenia gravis [ORDO Disease]
- Myasthenia gravis [ICD-10 Sub-category (who)]
- Myasthenia gravis [ICD-10 Sub-category]
- Myasthenia gravis (disorder) [SNOMED CT concept]
- Myasthenia gravis paralytica [MedDRA LLT]
- myasthenia gravis [DO Concept]
- myasthenia gravis [Disease (Nov.)]
- myasthenia gravis [MedlinePlus Topic]
- myasthenia gravis, nos [SNOMED Notion]
Validated automatic mappings to BTNT
- generalized myasthenia gravis [Disease (Nov.)]
- ocular myasthenia gravis [Disease (Nov.)]

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